| Entity | State or other Jurisdiction of Incorporation or Organization | |||||||
| Agios Securities Corporation | Massachusetts | |||||||
| Agios Limited | Bermuda | |||||||
| Agios International Sarl (GmbH) | Switzerland | |||||||
| Agios Netherlands B.V. | The Netherlands | |||||||
| Agios Germany GmbH | Germany | |||||||
| Agios Italy S.R.L. | Italy | |||||||
| Agios France SARL | France | |||||||