May 26, 2026 Scott Hutton Chief Executive Officer Biodesix, Inc. 919 West Dillon Road Louisville, CO 80027 Re: Biodesix, Inc. Registration Statement on Form S-3 Filed May 21, 2026 File No. 333-296122 Dear Scott Hutton: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Nicholas O'Leary at 202-551-4451 with any questions. Sincerely, Division of Corporation Finance Office of Industrial Applications and Services cc: Frank Rahmani, Esq.