SCHEDULE 13G 0001441449 XXXXXXXX LIVE Common Stock SH 06/11/2025 0002036042 Sionna Therapeutics Inc 829401108 21 Hickory Drive, Suite 500 Waltham MA 02451 Rule 13d-1(c) Qatar Investment Authority S3 2209775.00 0.00 2209775.00 0.00 2209775.00 N 5.0 OO Q Healthcare Holding LLC S3 2209775.00 0.00 2209775.00 0.00 2209775.00 N 5.0 IV Sionna Therapeutics Inc 21 Hickory Drive, Suite 500, Waltham, MA 02451, US Qatar Investment Authority | Q Healthcare Holding LLC Qatar Investment Authority - Ooredoo Tower (Building 14), Al Dafna Street (Street 801), Al Dafna (Zone 61), Doha, Qatar | Q Healthcare Holding LLC - Ooredoo Tower (Building 14) Al Dafna Street (Street 801) Al Dafna (Zone 61), Doha, Qatar Qatar Investment Authority - Qatar Q Healthcare Holding LLC - Qatar N OO 2,209,775 5.0 2,209,775 0 2,209,775 0 Y Y Y Y Y N By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11. Qatar Investment Authority Andrew Watkins 06/15/2025 Q Healthcare Holding LLC Andrew Watkins 06/15/2025