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Exhibit 31.1

PRINCIPAL EXECUTIVE OFFICER CERTIFICATION 

I, William D. Clark, certify that:

1.I have reviewed this Amendment No.1 to the Annual Report on Form 10-K of Genocea Biosciences, Inc.; and

2.Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report.

 

						/s/ WILLIAM D. CLARK
						William D. Clark
						President and Chief Executive Officer and Director
						(Principal Executive Officer)
Date:			April 29, 2022