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EXHIBIT 1

JOINT FILING AGREEMENT

The undersigned hereby agree that the statement on Schedule 13D with respect to the common stock of Soleno Therapeutics Inc. dated as of January 12, 2018 is, and any amendments thereto (including amendments on Schedule 13G) signed by each of the undersigned shall be, filed on behalf of each of us pursuant to and in accordance with the provisions of Rule 13d-1(k) under the Securities Exchange Act of 1934.

 

Jack W. Schuler Living Trust
/s/ Jack W. Schuler
  Name:   Jack W. Schuler
  Title:   Trustee
Schuler Grandchildren LLC
/s/ Jack W. Schuler
  Name:   Jack W. Schuler
  Title:   Manager
Tino Hans Schuler Trust
/s/ H. George Schuler
  Name:   H. George Schuler
  Title:   Trustee
Tanya Eva Schuler Trust
/s/ H. George Schuler
  Name:   H. George Schuler
  Title:   Trustee
Therese Heidi Schuler Trust
/s/ H. George Schuler
  Name:   H. George Schuler
  Title:   Trustee
Schuler Grandchildren 2010 Continuation Trust
/s/ H. George Schuler
  Name:   H. George Schuler
  Title:   Trustee

January 12, 2018