EXHIBIT 1
JOINT FILING AGREEMENT
The undersigned hereby agree that the statement on Schedule 13D with respect to the common stock of Soleno Therapeutics Inc. dated as of January 12, 2018 is, and any amendments thereto (including amendments on Schedule 13G) signed by each of the undersigned shall be, filed on behalf of each of us pursuant to and in accordance with the provisions of Rule 13d-1(k) under the Securities Exchange Act of 1934.
| Jack W. Schuler Living Trust |
| /s/ Jack W. Schuler |
| Name: Jack W. Schuler |
| Title: Trustee |
| Schuler Grandchildren LLC |
| /s/ H. George Schuler |
| Name: H. George Schuler |
| Title: Manager |
| Tino Hans Schuler Trust |
| /s/ Tino Hans Schuler |
| Name: Tino Hans Schuler |
| Title: Trustee |
| Tanya Eva Schuler Trust |
| /s/ H. George Schuler |
| Name: H. George Schuler |
| Title: Trustee |
| Therese Heidi Schuler Trust |
| /s/ H. George Schuler |
| Name: H. George Schuler |
| Title: Trustee |
| Schuler Grandchildren 2010 Continuation Trust |
| /s/ H. George Schuler |
| Name: H. George Schuler |
| Title: Trustee |
December 7, 2018