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    <submissionType>N-PX</submissionType>
    <filerInfo>
      <registrantType>RMIC</registrantType>
      <liveTestFlag>LIVE</liveTestFlag>
      <filer>
        <issuerCredentials>
          <cik>0001490286</cik>
          <ccc>XXXXXXXX</ccc>
        </issuerCredentials>
      </filer>
      <investmentCompanyType>N-2</investmentCompanyType>
      <periodOfReport>12/20/2024</periodOfReport>
    </filerInfo>
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  <formData>
    <coverPage>
      <yearOrQuarter>YEAR</yearOrQuarter>
      <reportCalendarYear>2025</reportCalendarYear>
      <reportingPerson>
        <name>Tortoise Midstream Energy Fund, Inc.</name>
        <phoneNumber>913-981-1020</phoneNumber>
        <address>
          <com:street1>6363 College Boulevard, Suite 100A</com:street1>
          <com:city>Overland Park</com:city>
          <com:stateOrCountry>KS</com:stateOrCountry>
          <com:zipCode>66211</com:zipCode>
        </address>
      </reportingPerson>
      <agentForService>
        <name>Matthew G.P. Sallee</name>
        <address>
          <com:street1>U.S. Bancorp Fund Services, LLC</com:street1>
          <com:street2>6363 College Boulevard, Suite 100A</com:street2>
          <com:city>Overland Park</com:city>
          <com:stateOrCountry>KS</com:stateOrCountry>
          <com:zipCode>66211</com:zipCode>
        </address>
      </agentForService>
      <reportInfo>
        <reportType>FUND NOTICE REPORT</reportType>
      </reportInfo>
      <fileNumber>811-21462</fileNumber>
      <explanatoryInformation>
        <explanatoryChoice>N</explanatoryChoice>
      </explanatoryInformation>
    </coverPage>
    <seriesPage>
      <seriesCount>0</seriesCount>
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    <signaturePage>
      <reportingPerson>Tortoise Midstream Energy Fund, Inc.</reportingPerson>
      <txSignature>Matthew G.P. Sallee</txSignature>
      <txPrintedSignature>Matthew G.P. Sallee</txPrintedSignature>
      <txTitle>Principal Executive Officer</txTitle>
      <txAsOfDate>08/26/2025</txAsOfDate>
    </signaturePage>
  </formData>
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