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Exhibit 107

Calculation of Filing Fee Tables

424(b)(5)

(Form Type)

Apellis Pharmaceuticals, Inc.

(Exact Name of Registrant as Specified in its Charter)

Table 1: Newly Registered and Carry Forward Securities

 

                 
     Security
Type
  Security
Class
Title
 

Fee
Calculation
or Carry
Forward

Rule

  Amount
Registered
 

Proposed
Maximum

Offering
Price Per

Unit

 

Maximum

Aggregate

Offering

Price

 

Fee

Rate

 

Amount of
Registration

Fee

 
Newly Registered Securities
                 

Fees to be

Paid

  Equity   Common Stock, par value $0.0001 per share   457(r)   6,388,892(1)   $63.00   $402,500,196(1)   0.00011020   $44,355.53(2)
                 

Fees to be

Paid

  Equity   Pre-funded warrants to purchase common stock(3)   457(r)   2,380,956(1   $62.9999(4)   $—(5)   0.00011020   $—(2)
                 

Fees

Previously

Paid

                 
 
Carry Forward Securities
                 

Carry

Forward

Securities

                 
           
    Total Offering Amounts      $402,500,196     $44,355.53
           
    Total Fees Previously Paid          $—
           
    Total Fee Offsets          $27,810(6)
           
    Net Fee Due                $16,545.53(6)

Table 2: Fee Offset Claims and Sources

 

                       
    

Registrant

or Filer

Name

  Form
or
Filing
Type
 

File

Number

 

Initial

Filing

Date

 

Filing

Date

 

Fee

Offset

Claimed

 

Security

Type

Associated

with Fee

Offset

Claimed

  Security
Title
Associated
with Fee
Offset
Claimed
  Unsold
Securities
Associated
with Fee
Offset
Claimed
 

Unsold

Aggregate
Offering

Amount
Associated

with Fee

Offset

Claimed

 

Fee

Paid

with

Fee

Offset

Source

 
Rule 457(p)
                       

Fee Offset

Claims

  Apellis Therapeutics, Inc.   424(b)(5)   333-235830   January 20, 2022     $27,810(3)  

Common
Stock, par value $0.0001 per share

  (3)   (3)   $300,000,000  
                       

Fee Offset

Sources

  Apellis Therapeutics, Inc.   424(b)(5)   333-235830     January 20, 2022             $27,810(6)


(1)

Assumes exercise in full of the underwriters’ option to purchase up to 833,333 additional shares of common stock and includes 2,380,956 shares of common stock issuable upon exercise of the pre-funded warrants to purchase common stock.

(2)

In accordance with Rule 457(r) under the Securities Act. This “Calculation of Filing Fee Tables” table shall be deemed to update the “Calculation of Registration Fee” table in the registrant’s Registration Statement on Form S-3 (File No. 333-269899) in accordance with Rule 456(b) and 457(r) under the Securities Act of 1933

(3)

Pursuant to Rule 416 under the Securities Act, the pre-funded warrants to purchase common stock being registered hereunder include such indeterminate number of additional shares of common stock as may be issued after the date hereof as a result of share splits, share dividends or similar transactions.

(4)

The registration fee for the pre-funded warrants is being allocated to the shares of common stock issuable upon exercise of the pre-funded warrants.

(5)

Represents the sum of the public offering price of the pre-funded warrants of $62.9999 per pre-funded warrant and the exercise price of $0.0001 per share issuable pursuant to the pre-funded warrants.

(6)

On January 20, 2022, the registrant filed a prospectus supplement dated January 20, 2022 pursuant to Rule 424(b(5) of the Securities Act (the “2022 prospectus supplement”), which supplemented the base prospectus included in the registrant’s registration statement on Form S-3 (File No. 333-235830) filed on January 7, 2020. The registrant registered an aggregate of $300,000,000 of securities under the 2022 prospectus supplement, representing $27,810 in registration fees, and sold $0 of securities under the 2022 prospectus supplement. The offering under the 2022 prospectus supplement been terminated.

Pursuant to Rule 457(p) under the Securities Act, the registration fee applicable to the securities being registered hereby in the amount of $44,355.53 is offset by $27,810 in registration fees previously paid by the registrant with respect to 2022 prospectus supplement that were registered but not sold prior to termination of the offering. Accordingly, $16,545.53 in registration fees are being paid in connection with this prospectus supplement