| Item 1. | |
| (a) | Name of issuer:
OnKure Therapeutics, Inc. |
| (b) | Address of issuer's principal executive offices:
6707 Winchester Circle #400 Boulder, CO 80301 |
| Item 2. | |
| (a) | Name of person filing:
The name of the persons filing this report (the "Reporting Persons") are:
(i) StepStone Group LP ("StepStone");
(ii) StepStone Master G, L.P. ("Master G"); and
(iii) StepStone VC MI-G GP, LLC ("MI-G GP").
MI-G GP is the general partner of Master G. StepStone is the sole managing member of MI-G GP. StepStone is the investment manager of each of Master G and MI-G GP. StepStone Group Holdings LLC ("StepStone Group Holdings") is the general partner of StepStone, and StepStone Group Inc. is the sole managing member of StepStone Group Holdings. |
| (b) | Address or principal business office or, if none, residence:
The address of the principal business office of each of the Reporting Persons is:
4225 Executive Square, Suite 1600
La Jolla, CA 92037 |
| (c) | Citizenship:
Each of StepStone and Master G is a limited partnership organized under the laws of the State of Delaware. MI-G GP is a limited liability company organized under the laws of the State of Delaware. |
| (d) | Title of class of securities:
Class A Common Stock, par value $0.0001 per share |
| (e) | CUSIP No.:
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| Item 3. | If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a: |
| (a) |  Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);
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| (b) | Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
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| (c) | Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);
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| (d) | Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
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| (e) | An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);
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| (f) | An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);
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| (g) | A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);
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| (h) | A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
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| (i) | A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
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| (j) | A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J). If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J),
please specify the type of institution:
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| (k) | Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).
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| | |
| Item 4. | Ownership |
| (a) | Amount beneficially owned:
The information required by this item with respect to each Reporting Person is set forth in Rows 5 through 9 and 11 of the cover page to this Schedule 13G. The ownership percentages are based on 40,395,478 shares of Common Stock outstanding as of April 1, 2026, as provided by the Issuer. |
| (b) | Percent of class:
See Item 4(a) above |
| (c) | Number of shares as to which the person has:
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| | (i) Sole power to vote or to direct the vote:
See Item 4(a) above
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| | (ii) Shared power to vote or to direct the vote:
See Item 4(a) above
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| | (iii) Sole power to dispose or to direct the disposition of:
See Item 4(a) above
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| | (iv) Shared power to dispose or to direct the disposition of:
See Item 4(a) above
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| Item 5. | Ownership of 5 Percent or Less of a Class. |
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Not Applicable
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| Item 6. | Ownership of more than 5 Percent on Behalf of Another Person. |
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Not Applicable
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| Item 7. | Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person. |
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Not Applicable
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| Item 8. | Identification and Classification of Members of the Group. |
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Not Applicable
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| Item 9. | Notice of Dissolution of Group. |
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Not Applicable
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Rule 13d-1(c)