Exhibit 23.1
Consent of Independent Registered Public Accounting Firm
We consent to the incorporation by reference in the following Registration Statements:
1.
Registration Statement (Form S-8, File No. 333-194746) pertaining to the 2010 Stock Incentive Plan, the 2013 Stock Incentive Plan, and the 2013 Employee Stock Purchase Plan of Karyopharm Therapeutics Inc.;
2.
Registration Statements (Form S-8, File Nos. 333-253469; 333-202742, 333-216732, and 333-223675) pertaining to the 2013 Stock Incentive Plan of Karyopharm Therapeutics Inc.;
3.
Registration Statements (Form S-8, File Nos. 333-210221, 333-229971 and 333-237160) pertaining to the 2013 Stock Incentive Plan and the 2013 Employee Stock Purchase Plan of Karyopharm Therapeutics Inc.;
4.
Registration Statement (Form S-8, File No. 333-226639) pertaining to Inducement Stock Option Awards (September 2017 – July 2018) of Karyopharm Therapeutics Inc.;
5.
Registration Statement (Form S-8, File No. 333-233094) pertaining to Inducement Stock Option Awards (August 2018 – July 2019) of Karyopharm Therapeutics Inc.;
6.
Registration Statement (Form S-8, File No. 333-248357) pertaining to Inducement Stock Option Awards (August 2019 – July 2020) of Karyopharm Therapeutics Inc.;
7.
Registration Statement (Form S-8, File No. 333-258513) pertaining to Inducement Stock Option Awards (August 2020 – July 2021) of Karyopharm Therapeutics Inc.;
8.
Registration Statement (Form S-8, File No. 333- 263075) pertaining to the 2013 Stock Incentive Plan, the 2013 Employee Stock Purchase Plan, the 2022 Inducement Stock Incentive Plan and Inducement Stock Option Awards (August 2021 – January 2022) of Karyopharm Therapeutics Inc.;
9.
Registration Statement (Form S-3, File No. 333-268991) and related Prospectus of Karyopharm Therapeutics Inc. for the registration of common stock;
10.
Registration Statement (Form S-8, File No. 333-265386) pertaining to the 2022 Equity Incentive Plan and 2022 Inducement Stock Incentive Plan, as amended, of Karyopharm Therapeutics Inc.;
11.
Registration Statement (Form S-8, File No. 333-269845) pertaining to the 2013 Employee Stock Purchase Plan and 2022 Inducement Stock Incentive Plan, as amended, of Karyopharm Therapeutics Inc.;
12.
Registration Statement (Form S-3, File No. 333-269846) and related Prospectus of Karyopharm Therapeutics Inc. for the registration of debt securities, common stock, preferred stock, warrants and/or units;
13.
Registration Statement (Form S-8, File No. 333-273593) pertaining to the Amended and Restated 2013 Employee Stock Purchase Plan and the 2022 Equity Incentive Plan, as amended, of Karyopharm Therapeutics Inc.;
14.
Registration Statement (Form S-3, File No. 333-279833) and related Prospectus of Karyopharm Therapeutics Inc. for the registration of common stock;
15.
Registration Statement (Form S-8, File No. 333-279823) pertaining to the Amended & Restated 2013 Employee Stock Purchase Plan, as amended, and the 2022 Equity Incentive Plan, as amended, of Karyopharm Therapeutics Inc.;
16.
Registration Statement (Form S-8, File No. 333-282994) pertaining to the 2022 Inducement Stock Incentive Plan, as amended, of Karyopharm Therapeutics Inc;