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Alkermes Contacts: |
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For Investors: |
Sandy Coombs +1 781 609 6377 |
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For Media: |
Katie Joyce +1 781 249 8927 |
Alkermes plc Reports Financial Results for the Fourth Quarter and Year Ended Dec. 31, 2025 and Provides Financial Expectations for 2026
— Total Revenues of $1.48 Billion in 2025; Net Sales of Proprietary Products Increased Approximately 9% Year-Over-Year —
— GAAP Net Income of $242 Million and Diluted GAAP Earnings per Share of $1.43 for 2025 —
— Alixorexton Phase 3 Clinical Program in Narcolepsy Expected to Initiate in Q1 2026 —
— Recent Completion of Avadel Acquisition Strengthens Leadership Position in Sleep Medicine —
DUBLIN, Feb. 25, 2026 — Alkermes plc (Nasdaq: ALKS) today reported financial results for the quarter and year ended Dec. 31, 2025 and provided financial expectations for 2026.
“Enabled by our strong operational and financial performance in 2025, Alkermes enters 2026 in a position of great strength, both financially and in terms of the opportunity to create value for shareholders through the development of important new medicines with significant market potential,” said Richard Pops, Chief Executive Officer of Alkermes. “As we look ahead, our strategic priorities for the year are clear: drive strong performance across our portfolio of commercial products, including LUMRYZ® (sodium oxybate) following the recently completed acquisition of Avadel; for alixorexton, initiate phase 3 studies designed to support a best-in-class profile in narcolepsy and complete our phase 2 study in idiopathic hypersomnia; and advance additional orexin candidates into phase 2 development in attention-deficit hyperactivity disorder and fatigue associated with multiple sclerosis and Parkinson’s disease. With strong momentum and a clear strategic vision, we are well positioned to deliver meaningful innovation and drive value in the years ahead.”
“In 2025, we generated total revenue of approximately $1.48 billion, strong profitability and cash flow. These results highlight the strength of our commercial portfolio and our continued focus on disciplined expense management,” said Joshua Reed, Chief Financial Officer of Alkermes. “As reflected in our financial expectations, in 2026 we are poised to drive robust cash generation and profitability while rapidly advancing alixorexton in registrational studies and progressing the clinical program for additional orexin 2 receptor agonists in our portfolio. The completed acquisition of Avadel enhances our financial profile, broadens our commercial capabilities, and accelerates our entry into the sleep medicine market. This positions us well for the potential future launch of alixorexton. With a solid balance sheet, a diversified revenue base, and a focused capital allocation strategy, we believe Alkermes is well‑positioned to deliver long-term growth and shareholder value.”
Key Financial Highlights
Revenues
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Three Months Ended December 31, |
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Twelve Months Ended December 31, |
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(In millions) |
2025 |
2024 |
|
2025 |
2024 |
||||
Total Revenues |
$ |
384.5 |
$ |
430.0 |
|
$ |
1,475.9 |
$ |
1,557.6 |
Total Proprietary Net Sales |
$ |
315.5 |
$ |
307.7 |
|
$ |
1,184.6 |
$ |
1,083.5 |
VIVITROL® |
$ |
124.1 |
$ |
134.1 |
|
$ |
467.9 |
$ |
457.3 |
ARISTADA®i |
$ |
97.2 |
$ |
96.6 |
|
$ |
370.0 |
$ |
346.2 |
LYBALVI® |
$ |
94.1 |
$ |
77.0 |
|
$ |
346.7 |
$ |
280.0 |