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Exhibit 21.1

LANTHEUS HOLDINGS, INC.

SUBSIDIARIES

Subsidiary

State or Other Jurisdiction of Organization

27 Commerce Street LLC

New Jersey

ACP Lantern Real Estate, LLC

Delaware

Aphelion LLC

Delaware

Cerveau Technologies, Inc.

Delaware

Evergreen Discovery, LLC

Delaware

Evergreen Theragnostics, Inc.

Delaware

Excelsior Life Sciences Ireland Limited

Ireland

EXINI Diagnostics AB

Sweden

Lantheus Alpha Therapy, LLC

Delaware

Lantheus EU Limited

Ireland

Lantheus Five, LLC

Delaware

Lantheus Medical Imaging, Inc.

Delaware

Lantheus MI Canada, Inc.

Canada

Lantheus MI Intermediate, Inc.

Delaware

Lantheus MI Real Estate, LLC

Delaware

Lantheus MI UK Limited

United Kingdom

Lantheus Omega, LLC

Delaware

Lantheus One, LLC

Delaware

Lantheus Radiopharmaceuticals UK Limited

United Kingdom

Lantheus Switzerland GmbH

Switzerland

Lantheus Three, LLC

Delaware

Lantheus Two, LLC

Delaware

Life Molecular Imaging GmbH

Germany

Life Molecular Imaging LLC

Delaware

Life Molecular Imaging Limited

United Kingdom

Meilleur Technologies, Inc.

Delaware

MNTX Royalties Sub LLC

Delaware

Molecular Insight Pharmaceuticals, Inc.

Delaware

Progenics Pharmaceuticals Nevada, Inc.

Nevada

Progenics Pharmaceuticals, Inc.

Delaware

PSMA Development Company LLC

Delaware

SPECT HoldCo LLC

Delaware