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SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

SCHEDULE 13G

UNDER THE SECURITIES EXCHANGE ACT OF 1934

(Name of Issuer)

(Title of Class of Securities)

(CUSIP Number)

(Date of Event Which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

Rule 13d-1(b)

Rule 13d-1(c)

Rule 13d-1(d)

X0202 SCHEDULE 13D/A 0001193125-23-085803 0001971787 XXXXXXXX LIVE 4 Common Stock, par value $0.0001 per share 06/25/2026 0001534133 38942Q202 CALCIMEDICA, INC. 505 Coast Boulevard South, Suite 307 La Jolla CA 92037 Valence Investments SPV IV LLC (212) 521-4379 590 Madison Avenue, 21st Floor New York NY 10022 Valence Investment SPV VI LLC (650) 565-2252 Dorsey & Whitney LLP 430 Cowper Street, Suite 250 Palo Alto NY 94301 Valence Investment SPV VI LLC (212) 521-4379 590 Madison Avenue, 21st Floor New York NY 10022 Eric Roberts (212) 521-4379 590 Madison Avenue, 21st Floor New York NY 10022 Rachel Leheny (212) 521-4379 590 Madison Avenue, 21st Floor New York NY 10022 Evan Ng (650) 565-2252 Dorsey & Whitney LLP 430 Cowper Street, Suite 250 Palo Alto CA 94301 0001812080 N Valence Investments SPV IV, LLC OO DE 0 356989 0 356989 356989 1.2 PN The calculation of percentage ownership is based on a total of 30,736,401 shares of Issuer common stock as of June 25, 2026, as set forth by the Issuer. 0001854361 N Valence Investments SPV V, LLC OO DE 0 86098 0 86098 86098 0.3 PN (1) Includes 66,228 shares of common stock and 19,870 immediately exercisable warrants to purchase common stock at an exercise price of $27.94 per share received pursuant to the Merger Agreement. (2) The calculation of percentage ownership is based on a total of 30,736,401 shares of Issuer common stock as of June 25, 2026, as set forth by the Issuer. 0001971787 N Valence Investments SPV VI, LLC OO DE 0 316109 0 316109 316109 1.0 PN The calculation of percentage ownership is based on a total of 30,736,401 shares of Issuer common stock as of June 25, 2026, as set forth by the Issuer. 0001576244 N Eric W. Roberts PF X1 1206720 759196 1206720 759196 1965916 6.4 IN (1) Includes 366,435 shares of common stock held directly by Mr. Roberts, 144,705 shares of common stock held in individual retirement accounts for the benefit of Mr. Roberts,317,608 Employee Stock Options to purchase common stock at an exercise price ranging from $0.585 to $17.34, and 421,143 warrants to purchase common stock at an exercise price ranging from $0.8033 to $10.42 per share. (2) Includes 19,870 warrants to purchase common stock at an exercise price of $27.94 held by Valence Investments SPV V, LLC, 356,989 shares of common stock held by Valence Investments SPV IV, LLC, 66,228 shares of common stock held by Valence Investments SPV V, LLC, and 316,109 shares of common stock held by Valence Investments SPV VI, LLC. Mr. Roberts is a co-founder and managing director of Valence Investments SPV IV, LLC, Valence Investments SPV V, LLC, and Valence Investments SPV VI, LLC. (3) The calculation of percentage ownership is based on a total of 30,736,401 shares of Issuer common stock as of June 25, 2026, as set forth by the Issuer. 0001484729 N A. Rachel Leheny PF X1 1167151 759196 1167151 759196 1926347 6.3 IN IA (1) Includes 317,655 shares of common stock held directly by Ms. Leheny, 3,500 shares of common stock held by Ms. Leheny's revocable trust, 1,000 shares of common stock held by Ms. Leheny's spouse, 792,120 Employee Stock Options to purchase common stock at an exercise price ranging from $0.585 to $17.34, and 419,001 warrants to purchase common stock at an exercise price ranging from $0.8033 to $7.15 per share. (2) Includes 19,870 warrants to purchase common stock at an exercise price of $27.94 held by Valence Investments SPV V, LLC, 356,989 shares of common stock held by Valence Investments SPV IV, LLC, 66,228 shares of common stock held by Valence Investments SPV V, LLC, and 316,109 shares of common stock held by Valence Investments SPV VI, LLC. Ms. Leheny is a co-founder and managing director of Valence Investments SPV IV, LLC, Valence Investments SPV V, LLC, and Valence Investments SPV VI, LLC. (3) The calculation of percentage ownership is based on a total of 30,736,401 shares of Issuer common stock as of June 25, 2026, as set forth by the Issuer. Common Stock, par value $0.0001 per share CALCIMEDICA, INC. 505 Coast Boulevard South, Suite 307 La Jolla CA 92037 Reference is hereby made to the statements on Schedule 13D originally filed with the Securities and Exchange Commission (the "SEC") on March 30, 2023, as amended by Amendment No 1 filed with the SEC on November 22, 2023, Amendment No 2 filed with the SEC on February 8, 2024 and Amendment No 3 filed with the SEC on November 6, 2024 (collectively, the "Schedule 13D"), which is incorporated by reference. This Amendment No 4 to the Schedule 13D filed, relating to the common stock, par value $0.0001 per share (the "Common Stock") of CalciMedica, Inc., a Delaware corporation (the "Issuer") amends and supplements certain of the items set forth therein. Item 3 is hereby amended supplemented by adding the following at the end of Item 3: Open-Market Purchases Since November 6, 2024, Mr. Roberts and Ms. Leheny have made purchases of Common Stock in open market transactions using their personal funds. Such transactions are described in greater detail in Item 5 below. Securities Purchase Agreement On June 23,2026, the Issuer entered into a Securities Purchase Agreement underwriting agreement with existing institutional and accredited investors relating to the issuance and sale in a public offering of 18,673,429 Units, each Unit comprised of one share of the Issuer's Common Stock, and one pre-funded warrant to purchase one share of Common Stock. The price in the offering was $0.8033 per Unit. Mr. Roberts and Ms. Leheny purchased 186,729 Units. The offering closed on June 25, 2026. Mr. Roberts and Ms. Leheny each used personal funds to acquire the Units. Item 5 is hereby amended and supplemented as follows: The Reporting Persons effected the following transactions in the Common Stock on the dates indicated, and such transactions are the only transactions in the Common Stock by the Reporting Persons in the sixty days preceding the filing of this Amendment, or since the last 13D filing, whichever is less: Name Nature of Transaction Date Number of Shares of Common Stock Price per Share Roberts Open Market Purchase 6/5/2025 5,100 $1.6638 to 1.7274 Roberts Open Market Purchase 6/6/2025 5,000 $1.75 to 1.87 Roberts Open Market Purchase 6/11/2025 5,000 $1.85 Roberts Open Market Purchase 6/26/2025 4,500 $1.43 to $1.4499 Roberts Open Market Purchase 7/09/2025 5,000 $1.6047 Leheny Open Market Purchase 7/14/2025 2,500 $2.47 Roberts Open Market Purchase 7/14/2025 6,500 $2.30 to $2.55 Roberts Open Market Purchase 7/18/2025 2,000 $2.88 Leheny Open Market Purchase 7/21/2025 1,000 $3.40 Roberts Open Market Purchase 7/21/2025 1,500 $3.37 Roberts Open Market Purchase 7/22/2025 1,500 $3.775 Roberts Open Market Purchase 8/15/2025 5,076 $2.8977 Roberts Option Exercise 8/20/2025 15,000 $1.53 Roberts Open Market Purchase 8/19/2025 1,000 $2.79 Roberts Open Market Purchase 8/20/2025 2,000 $2.72 Roberts Open Market Purchase 8/21/2025 3,508 $2.75 to 2.80 Roberts Open Market Purchase 8/28/2025 9,200 $2.75 to $2.92 Roberts Open Market Purchase 8/29/2025 800 $2.74 Roberts Open Market Purchase 9/9/2025 2,343 $2.75 to $3.21 Roberts Open Market Purchase 9/12/2025 5,000 $3.12 Roberts Open Market Purchase 9/15/2025 3,400 $2.65 to $2.70 Roberts Open Market Purchase 9/18/2025 2,500 $3.07 Leheny Purchase in Private Placement 6/25/2026 186,729 $0.8033 Roberts Purchase in Private Placement 6/25/2026 186,729 $0.8033 Valence Investments SPV IV, LLC /s/ Eric Roberts Eric Roberts, Manager 06/30/2026 Valence Investments SPV V, LLC /s/ Eric Roberts Eric Roberts, Manager 06/30/2026 Valence Investments SPV VI, LLC /s/ Eric Roberts Eric Roberts, Manager 06/30/2026 Eric W. Roberts /s/ Eric Roberts Self 06/30/2026 A. Rachel Leheny /s/ Rachel Leheny Self 06/30/2026