Exhibit 21.1
SUBSIDIARIES OF REGISTRANT
| Subsidiary | Country / State of Incorporation |
| Xenetic Biosciences (UK), Ltd. | United Kingdom registered company |
| Lipoxen Technologies, Ltd. | United Kingdom registered company |
| Xenetic Bioscience, Inc. | Delaware |
| SymbioTec, GmbH | German registered company |
| Hesperix S.A. | Swiss registered company |