EXHIBIT 23.1

CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM

The Board of Directors

Lipocine Inc.:

We consent to the incorporation by reference in the registration statements (Nos. 333-250072, 333-190897, 333-240197, 333-226664, 333-214492, 333-197421, 333-191695 and 333-275716) on Forms S-3 and S-8 of Lipocine Inc. of our report dated March 10, 2026 with respect to the consolidated balance sheets of Lipocine Inc. as of December 31, 2025 and 2024, and the related consolidated statements of operations and comprehensive loss, changes in stockholders’ equity, and cash flows for the years then ended, and the related notes (collectively, the “consolidated financial statements”), which report appears in the December 31, 2025 annual report on Form 10-K of Lipocine Inc.