United States securities and exchange commission logo August 1, 2022 John Temperato Chief Executive Officer 9 Meters Biopharma, Inc. 8480 Honeycutt Road, Suite 120 Raleigh, NC 27615 Re: 9 Meters Biopharma, Inc. Registration Statement on Form S-3 Filed July 28, 2022 File No. 333-266377 Dear Mr. Temperato: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Christine Westbrook at 202-551-5019 with any questions. Sincerely, Division of Corporation Finance Office of Life Sciences cc: Lorna Knick, Esq.