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Exhibit 107

Calculation of Filing Fee Tables

424(b)(5)

(Form Type)

Prothena Corporation plc

(Exact Name of Registrant as Specified in its Charter)

Table 1: Newly Registered and Carry Forward Securities

 

                         
     Security
Type
  Security
Class Title
  Fee
Calculation or
Carry
Forward Rule
  Amount
Registered
  Proposed
Maximum
Offering
Price Per
Share
  Maximum
Aggregate
Offering Price
  Fee Rate   Amount of
Registration
Fee(1)
 

Carry

Forward

Form

Type

 

Carry

Forward

File

Number

 

Carry

Forward

Initial

effective

date

 

Filing Fee

Previously

Paid In

Connection

with
Unsold

Securities
to be
Carried

Forward

                         
Fees to Be Paid   Equity   Ordinary Shares, $0.01 par value per share   457(o) and 457(r)   3,737,500(2)   56.50   $211,168,750   0.00011020   $23,271        
                         
Fees Previously Paid                          
 
Carry Forward Securities
                         
Carry Forward Securities                        
                   
    Total Offering Amounts     $211,168,750     $23,271          
                   
    Total Fees Previously Paid                  
                   
    Total Fee Offsets                  
                   
    Net Fee Due               $23,271                
(1)

Calculated in accordance with Rules 457(o) and 457(r) under the Securities Act of 1933, as amended (the “Securities Act”). In accordance with Rules 456(b) and 457(r) of the Securities Act, as amended, the registrant initially deferred payment of all of the registration fee for Registration Statement No. 333-254622 filed by the registrant on March 23, 2021.

(2)

Includes 487,500 ordinary shares that the underwriters have an option to purchase.