SCHEDULE 13G 0001756235 XXXXXXXX LIVE Common Stock, par value $0.00001 per share 12/31/2024 0001562733 Synergy CHC Corp. 87165D208 865 Spring Street Westbrook ME 04092 Rule 13d-1(d) KNIGHT THERAPEUTICS INC. Z4 1482844.00 0.00 1482844.00 0.00 1482844.00 N 17.03 CO (1) Calculated based on 8,703,818 shares of common stock issued and outstanding as of December 2, 2024, as disclosed by the Issuer in its quarterly report on Form 10-Q filed by the Issuer on December 6, 2024. See Item 4(b) below. Synergy CHC Corp. 865 Spring Street Westbrook, Maine 04092 Knight Therapeutics Inc. 3400 de Maisonneuve W. Suite 1055, Montreal, Quebec, H3Z 3B8, Canada See Row 4 of the cover pages for the citizenship or place of organization of the Reporting Person Y 1,482,844 As of the date hereof, the Reporting Person owns directly 1,096,693 shares of common stock of the Issuer. The remaining 386,151 shares of common stock of the Issuer are held by Knight Therapeutics International S.A. ("Knight Subsidiary"), a wholly-owned subsidiary of the Reporting Person. The Reporting Person is the sole owner of Knight Subsidiary and, as a result, may be deemed the beneficial owner for purposes of the Act of any securities of Issuer beneficially owned by Knight Subsidiary. The Reporting Person disclaims beneficial ownership over all of the shares of common stock of Issuer beneficially owned by Knight Subsidiary, other than for the purpose of determining obligations under the Act, and the filing of this Schedule 13G shall not be deemed an admission that the Reporting Person is the beneficial owner of such securities for any other purpose. 17.03% The percentage of beneficial ownership is calculated based on 8,703,818 shares of common stock issued and outstanding as of December 2, 2024, as disclosed by the Issuer in its quarterly report on Form 10-Q filed by the Issuer on December 6, 2024. 1,482,844 0 1,482,844 0 Y Y Y Y Y Y KNIGHT THERAPEUTICS INC. /s/ Samira Sakhia 03/19/2025