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Exhibit 32.1 
CERTIFICATIONS UNDER SECTION 906 
Pursuant to section 906 of the Sarbanes-Oxley Act of 2002 (subsections (a) and (b) of section 1350, chapter 63 of title 18, United States Code), each of the undersigned officers of Intra-Cellular Therapies, Inc., a Delaware corporation (the “Company”), does hereby certify, to such officer’s knowledge, that: 
The Annual Report for the year ended December 31, 2023 (the “Form 10-K”) of the Company fully complies with the requirements of Section 13(a) or 15(d) of the Securities Exchange Act of 1934, and the information contained in the Form 10-K fairly presents, in all material respects, the financial condition and results of operations of the Company. 
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Dated: February 22, 2024  | /s/ Sharon Mates, Ph.D. | 
 | Sharon Mates, Ph.D. | 
 | Chairman, President and Chief Executive Officer (principal executive officer) | 
Dated: February 22, 2024  | /s/ Lawrence J. Hineline | 
 | Lawrence J. Hineline | 
 | Senior Vice President of Finance and Chief Financial Officer (principal financial officer and principal accounting officer) |