Exhibit 8.1
SIGNIFICANT SUBSIDIARIES
Our significant subsidiaries are set forth below, all of which are either 100% owned by us or controlled by us.
| Legal Name | Jurisdiction | |
| Kamada Biopharma Limited | England and Wales | |
| Kamada Inc. | Delaware | |
| Kamada Ireland Limited | Ireland | |
| Kamada Assets (2001) Ltd. | Israel |