| | | | | | | | |
| Name of Subsidiary | | Jurisdiction of Incorporation/Organization |
| Cache Holdings Limited | | Bermuda |
| Carnforth Limited | | Bermuda |
| Dritte CORSA Verwaltungsgesellschaft GmbH | | Germany |
| Ikaria Australia Pty Ltd | | Australia |
| Ikaria Canada Inc. | | Canada |
| IMC Exploration Company | | Maryland |
| Infacare Pharmaceutical Corporation | | Delaware |
| INO Therapeutics LLC | | Delaware |
| Ludlow LLC | | Massachusetts |
| MAK LLC | | Delaware |
| Mallinckrodt APAP LLC | | Delaware |
| Mallinckrodt ARD Finance LLC | | Delaware |
| Mallinckrodt ARD Holdings Inc. | | Delaware |
| Mallinckrodt ARD Holdings Limited | | United Kingdom |
| Mallinckrodt ARD LLC | | California |
| Mallinckrodt Brand Pharmaceuticals LLC | | Delaware |
| Mallinckrodt Canada Cooperatie U.A. | | Netherlands |
| Mallinckrodt Canada ULC | | British Columbia |
| Mallinckrodt CB LLC | | Delaware |
| Mallinckrodt Chemical Holdings (U.K.) Limited | | United Kingdom |
| Mallinckrodt Chemical Limited | | United Kingdom |
| Mallinckrodt Critical Care Finance LLC | | Delaware |
| Mallinckrodt Enterprises Holdings LLC | | California |
| Mallinckrodt Enterprises LLC | | Delaware |
| Mallinckrodt Enterprises UK Limited | | United Kingdom |
| Mallinckrodt Equinox Finance LLC | | Delaware |
| Mallinckrodt Equinox Limited | | United Kingdom |
| Mallinckrodt Finance Management Ireland Limited | | Ireland |
| Mallinckrodt Group S.à r.l. | | Luxembourg |
| Mallinckrodt Group S.à r.l., Luxembourg (LU) Schaffhausen Branch | | Switzerland |
| Mallinckrodt Holdings GmbH | | Switzerland |
| Mallinckrodt Hospital Products Inc. | | Delaware |
| Mallinckrodt International Finance SA | | Luxembourg |
| Mallinckrodt International Holdings S. à r.l. | | Luxembourg |
| Mallinckrodt LLC | | Delaware |
| Mallinckrodt Lux IP S.à r.l. | | Luxembourg |
| Mallinckrodt Manufacturing LLC | | Delaware |
| Mallinckrodt Medical Holdings (UK) Limited | | United Kingdom |
| Mallinckrodt Medical Holdings (UK) Limited, Zweigniederlassung Deutschland (the German Branch) | | Germany |
| Mallinckrodt Netherlands B.V. | | Netherlands |
| Mallinckrodt Petten Holdings B.V. | | Netherlands |
| Mallinckrodt Pharma IP Trading Limited Company | | Ireland |
| Mallinckrodt Pharma K.K. | | Japan |
| Mallinckrodt Pharmaceuticals Ireland Limited | | Ireland |
| Mallinckrodt Pharmaceuticals Limited | | United Kingdom |
| Mallinckrodt Quincy S.à r.l. | | Luxembourg |
| Mallinckrodt SAG Holdings GmbH | | Switzerland |
| Mallinckrodt UK Finance LLP | | United Kingdom |
| Mallinckrodt UK Ltd | | United Kingdom |
| Mallinckrodt US Holdings LLC | | Delaware |