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Exhibit 107

Calculation of Filing Fee Tables

Form S-8

(Form Type)

Epizyme, Inc.

(Exact Name of Registrant as Specified in its Charter)

Table 1—Newly Registered Securities

 

               
Security
Type
  

Security

Class

Title

   Fee
Calculation 
Rule
   Amount
Registered (1) 
  Proposed 
Maximum 
Offering 
Price Per 
Unit
   Maximum 
Aggregate 
Offering Price 
 

Fee

Rate

   Amount of 
Registration 
Fee
               
Equity    Common 
Stock, 
$0.0001 
par value 
per share 
   Other    15,151,463 
shares (2) 
  $1.49 (3)     $22,575,680 (3)    $92.70

per
$1,000,000 

   $2,092.77 
         
Total Offering Amounts            $2,092.77 
         
Total Fee Offsets            $0
         
Net Fee Due                  $2,092.77 

 

(1)

In accordance with Rule 416 under the Securities Act of 1933, as amended, this registration statement shall be deemed to cover any additional securities that may from time to time be offered or issued to prevent dilution resulting from stock splits, stock dividends or similar transactions.

(2)

Consists of 15,151,463 shares issuable under the 2022 Equity Incentive Plan.

 

(3)

Estimated solely for the purpose of calculating the registration fee pursuant to Rules 457(c) and 457(h) of the Securities Act of 1933, as amended, and based upon the average of the high and low prices of the Registrant’s Common Stock as reported on the Nasdaq Global Select Market on August 2, 2022.