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S-8 S-8 EX-FILING FEES 0001576280 Guardant Health, Inc. N/A Fees to be Paid Fees to be Paid 0001576280 2026-02-17 2026-02-17 0001576280 1 2026-02-17 2026-02-17 0001576280 2 2026-02-17 2026-02-17 iso4217:USD xbrli:pure xbrli:shares

Calculation of Filing Fee Tables

S-8

Guardant Health, Inc.

Table 1: Newly Registered Securities

Security Type

Security Class Title

Fee Calculation Rule

Amount Registered

Proposed Maximum Offering Price Per Unit

Maximum Aggregate Offering Price

Fee Rate

Amount of Registration Fee

1 Equity Common Stock, $0.0001 par value per share, reserved for issuance pursuant to the 2018 Incentive Award Plan Other 3,689,000 $ 104.40 $ 385,131,600.00 0.0001381 $ 53,186.68
2 Equity Common Stock, $0.0001 par value per share, reserved for issuance pursuant to the 2018 Employee Stock Purchase Plan Other 1,106,700 $ 88.74 $ 98,208,558.00 0.0001381 $ 13,562.61

Total Offering Amounts:

$ 483,340,158.00

$ 66,749.29

Total Fee Offsets:

$ 0.00

Net Fee Due:

$ 66,749.29

Offering Note

1

Pursuant to Rule 416(a) under the Securities Act of 1933, as amended (the "Securities Act"), this Registration Statement shall also cover any additional shares of the Registrant's common stock that become issuable in respect of the securities identified in the above table by reason of any stock dividend, stock split, recapitalization or other similar transaction effected without the Registrant's receipt of consideration that increases the number of the outstanding shares of the Registrant's common stock. Represents additional shares of common stock reserved for issuance under the Registrant's 2018 Incentive Award Plan (the "2018 Plan") resulting from the annual automatic increase in the number of authorized shares reserved for issuance under the 2018 Plan. The increase was effective as of January 1, 2026. Estimated under Rules 457(c) and (h) of the Securities Act solely for the purpose of calculating the registration fee on the basis of the average of the high and low prices of the Registrant's common stock as quoted by The Nasdaq Global Market on February 12, 2026, which date is within five business days prior to the filing of the Registration Statement.

2

Pursuant to Rule 416(a) under the Securities Act, this Registration Statement shall also cover any additional shares of the Registrant's common stock that become issuable in respect of the securities identified in the above table by reason of any stock dividend, stock split, recapitalization or other similar transaction effected without the Registrant's receipt of consideration that increases the number of the outstanding shares of the Registrant's common stock. Represents additional shares of common stock reserved for issuance under the Registrant's 2018 Employee Stock Purchase Plan (the "2018 ESPP") resulting from the annual automatic increase in the number of authorized shares reserved for issuance under the 2018 ESPP. The increase was effective as of January 1, 2026. Estimated under Rules 457(c) and (h) of the Securities Act solely for the purpose of calculating the registration fee on the basis of the average of the high and low prices of the Registrant's common stock as quoted by The Nasdaq Global Market on February 12, 2026, which date is within five business days prior to the filing of the Registration Statement, multiplied by 85%, which is the percentage of the trading price per share applicable to purchasers under the 2018 ESPP.

Table 2: Fee Offset Claims and Sources ☑Not Applicable
Registrant or Filer Name Form or Filing Type File Number Initial Filing Date Filing Date Fee Offset Claimed Security Type Associated with Fee Offset Claimed Security Title Associated with Fee Offset Claimed Unsold Securities Associated with Fee Offset Claimed Unsold Aggregate Offering Amount Associated with Fee Offset Claimed Fee Paid with Fee Offset Source
Rule 457(p)
Fee Offset Claims N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
Fee Offset Sources N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A