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We consent to the incorporation by reference in the Registration Statement (Form S-8) pertaining to the Acumen Pharmaceuticals, Inc. 2021 Equity Incentive Plan and 2021 Employee Stock Purchase Plan of our report dated March 27, 2023, with respect to the financial statements of Acumen Pharmaceuticals, Inc., included in its Annual Report (Form 10-K) for the year ended December 31, 2022 filed with the Securities and Exchange Commission.