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Consent of Independent Registered Public Accounting Firm
We consent to the reference to our firm under the caption “Experts” in the Registration Statement (Form S-3) and related Prospectus of Acumen Pharmaceuticals, Inc. for the registration of its common stock and to the incorporation by reference therein of our report dated March 26, 2026, with respect to the financial statements of Acumen Pharmaceuticals, Inc. included in its Annual Report (Form 10-K) for the year ended December 31, 2025, filed with the Securities and Exchange Commission.
/s/ Ernst & Young LLP
| | |
| Philadelphia, Pennsylvania |
| March 26, 2026 |