Exhibit 23.1
CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM
The Board of Directors
Xenon Pharmaceuticals Inc.
We consent to the use of:
each of which is included in the Annual Report on Form 10-K of the Entity for the fiscal year ended December 31, 2023.
We also consent to the incorporation by reference of such reports in the Registration Statements (Nos. 333-199860, 333-202765, 333-210050, 333-216543, 333-223497, 333-230103, 333-233758, 333-237036, 333-238895, and 333-265377) on Form S-8, and (No. 333-260010) on Form S-3ASR of the Entity.
/s/ KPMG LLP
Chartered Professional Accountants
February 29, 2024
Vancouver, Canada