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Exhibit 22

Subsidiary Guarantors and Issuers of Guaranteed Securities and Affiliates Whose Securities Collateralize Securities of the Registrant

As of June 28, 2025, the obligors under (i) the 5.300% Notes due 2043 issued by the Company (the “Company Notes”) consisted of the subsidiaries listed in the following table and (ii) the 4.900% Notes due 2030, the 5.375% Euro Notes due 2032, the 6.125% USD Notes due 2032, and the 4.900% Notes due 2044 issued by Perrigo Finance Unlimited Company (collectively, the “Perrigo Finance Notes”) consisted of the Company, as a guarantor, and its subsidiaries listed in the following table.

Name of EntityObligor Type (Company Notes)Obligor Type (Perrigo Finance Notes)
Athena Neurosciences, LLCGuarantorGuarantor
Chefaro Ireland Designated Activity CompanyGuarantorGuarantor
Elan Pharmaceuticals, LLCGuarantorGuarantor
Galpharm Healthcare LimitedGuarantorGuarantor
Galpharm International LimitedGuarantorGuarantor
Gr8ness, LLCGuarantorGuarantor
L. Perrigo CompanyGuarantorGuarantor
Medgenix Benelux NVGuarantorGuarantor
OCE-BIO BVGuarantorGuarantor
Omega Pharma Innovation & Development NVGuarantorGuarantor
Omega Pharma International NVGuarantorGuarantor
Omega Pharma LimitedGuarantorGuarantor
Omega Pharma Trading NVGuarantorGuarantor
Omega Teknika Designated Activity Company
GuarantorGuarantor
PBM Canada Holdings, LLCGuarantorGuarantor
PBM Nutritionals, LLCGuarantorGuarantor
PBM Products, LLCGuarantorGuarantor
Perrigo Americas Holdings, IncGuarantorGuarantor
Perrigo Belgium NVGuarantorGuarantor
Perrigo Capital NVGuarantorGuarantor
Perrigo CompanyGuarantorGuarantor
Perrigo Company PlcIssuerGuarantor
Perrigo Corporation Designated Activity CompanyGuarantorGuarantor
Perrigo Diabetes Care, LLCGuarantorGuarantor
Perrigo Direct, Inc.GuarantorGuarantor
Perrigo Europe Invest NVGuarantorGuarantor
Perrigo Finance (US) LLCGuarantorGuarantor
Perrigo Finance Unlimited CompanyGuarantorIssuer
Perrigo Florida, Inc.GuarantorGuarantor
Perrigo Holding NVGuarantorGuarantor
Perrigo Holdings Unlimited CompanyGuarantorGuarantor
Perrigo International Finance Designated Activity CompanyGuarantorGuarantor
Perrigo International Holdings II, LLCGuarantorGuarantor
Perrigo International Holdings, LLCGuarantorGuarantor
Perrigo International, LLCGuarantorGuarantor


Perrigo Investments, LLCGuarantorGuarantor
Perrigo Ireland 1 Designated Activity CompanyGuarantorGuarantor
Perrigo Ireland 10 Unlimited CompanyGuarantorGuarantor
Perrigo Ireland 13 Designated Activity CompanyGuarantorGuarantor
Perrigo Ireland 2 Designated Activity CompanyGuarantorGuarantor
Perrigo Ireland 4 Unlimited CompanyGuarantorGuarantor
Perrigo Ireland 6 Limited CompanyGuarantorGuarantor
Perrigo Ireland 9 Unlimited Company
GuarantorGuarantor
Perrigo Management CompanyGuarantorGuarantor
Perrigo Mexico Investment Holdings, LLCGuarantorGuarantor
Perrigo New York, Inc.GuarantorGuarantor
Perrigo Pharma International Designated Activity CompanyGuarantorGuarantor
Perrigo Pharma LimitedGuarantorGuarantor
Perrigo Research & Development CompanyGuarantorGuarantor
Perrigo Sales CorporationGuarantorGuarantor
Perrigo Science One Designated Activity Company
GuarantorGuarantor
Perrigo Supply Chain International Designated Activity CompanyGuarantorGuarantor
Perrigo UK Acquisition LimitedGuarantorGuarantor
PMI Branded Pharmaceuticals, Inc.GuarantorGuarantor
Ranir Global Holdings, LLCGuarantorGuarantor
Ranir (Holdings) LimitedGuarantorGuarantor
Ranir, LLCGuarantorGuarantor
Wrafton Laboratories LimitedGuarantorGuarantor