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Check the appropriate box to designate the rule pursuant to which this Schedule is filed:
Checkbox not checked   Rule 13d-1(b)
Checkbox checked   Rule 13d-1(c)
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SCHEDULE 13G





SCHEDULE 13G




Comment for Type of Reporting Person:  Based on 20,902,104 Common Shares outstanding as reported by Alpha Cognition, Inc. in its Form 424B5 filed with the SEC on October 1, 2025.


SCHEDULE 13G





SCHEDULE 13G



 
Opaleye Management Inc.
 
Signature:/s/ James Silverman
Name/Title:President
Date:10/03/2025
 
Opaleye, L.P.
 
Signature:/s/ James Silverman
Name/Title:General Partner
Date:10/03/2025
 
James Silverman
 
Signature:/s/ James Silverman
Name/Title:Individually
Date:10/03/2025
Exhibit Information

Exhibit 99.1 Joint Filing Agreement by and among the reporting persons