Entity

State/Jurisdiction of Incorporation or Organization

Blueprint Medicines Security Corporation

Massachusetts

Blueprint Medicines (Switzerland) GmbH

Switzerland

Blueprint Medicines (Netherlands) B.V.

Netherlands

Blueprint Medicines (UK) Ltd.

United Kingdom

Blueprint Medicines (Germany) GmbH

Germany

Blueprint Medicines Spain, S.L.

Spain

Blueprint Medicines (France) SAS

France

Blueprint Medicines (Italy) S.r.L.

Italy