SEC FORM 4

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SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

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Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

Column Group IV GP, LP

(Last)

(First)

(Middle)

1 LETTERMAN DR., BLDG D, SUITE DM-900

(Street)

SAN FRANCISCO

94129

(City)

(State)

(Zip)

2. Issuer Name and Ticker or Trading Symbol
Eikon Therapeutics, Inc. [ EIKN ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

Director	X	10% Owner
Officer (give title below)		Other (specify below)

3. Date of Earliest Transaction (Month/Day/Year)
02/06/2026

4. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

	Form filed by One Reporting Person
X	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	Code	V	Amount	(A) or (D)	Price		6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
Common Stock	02/06/2026		C⁽¹⁾		1,296,629	A	⁽¹⁾	1,360,320	I	By The Column Group IV, LP⁽²⁾
Common Stock	02/06/2026		C⁽¹⁾		1,403,568	A	⁽¹⁾	2,763,888	I	By The Column Group IV, LP⁽²⁾
Common Stock	02/06/2026		C⁽¹⁾		110,928	A	⁽¹⁾	2,874,816	I	By The Column Group IV, LP⁽²⁾
Common Stock	02/06/2026		C⁽¹⁾		44,249	A	⁽¹⁾	47,601	I	By The Column Group IV-A, LP⁽³⁾
Common Stock	02/06/2026		C⁽¹⁾		47,898	A	⁽¹⁾	95,499	I	By The Column Group IV-A, LP⁽³⁾
Common Stock	02/06/2026		C⁽¹⁾		3,785	A	⁽¹⁾	99,284	I	By The Column Group IV-A, LP⁽³⁾
Common Stock	02/06/2026		C⁽¹⁾		688,283	A	⁽¹⁾	688,283	I	By The Column Group Opportunity III, LP⁽⁴⁾
Common Stock	02/06/2026		P		1,437,323	A	$18	4,312,139	I	By The Column Group IV, LP⁽²⁾
Common Stock	02/06/2026		P		49,556	A	$18	148,840	I	By The Column Group IV-A, LP⁽³⁾
Common Stock	02/06/2026		P		630,881	A	$18	1,319,164	I	By The Column Group Opportunity III, LP⁽⁴⁾

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares	8. Price of Derivative Security (Instr. 5)		10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
Series A Preferred Stock	⁽¹⁾	02/06/2026		C⁽¹⁾			9,670,000	⁽¹⁾	⁽¹⁾	Common Stock	1,296,629	⁽¹⁾	0	I	By The Column Group IV, LP⁽²⁾
Series A Preferred Stock	⁽¹⁾	02/06/2026		C⁽¹⁾			330,000	⁽¹⁾	⁽¹⁾	Common Stock	44,249	⁽¹⁾	0	I	By The Column Group IV-A, LP⁽³⁾
Series A-1 Preferred Stock	⁽¹⁾	02/06/2026		C⁽¹⁾			10,467,526	⁽¹⁾	⁽¹⁾	Common Stock	1,403,568	⁽¹⁾	0	I	By The Column Group IV, LP⁽²⁾
Series A-1 Preferred Stock	⁽¹⁾	02/06/2026		C⁽¹⁾			357,216	⁽¹⁾	⁽¹⁾	Common Stock	47,898	⁽¹⁾	0	I	By The Column Group IV-A, LP⁽³⁾
Series C-1 Preferred Stock	⁽¹⁾	02/06/2026		C⁽¹⁾			827,278	⁽¹⁾	⁽¹⁾	Common Stock	110,928	⁽¹⁾	0	I	By The Column Group IV, LP⁽²⁾
Series C-1 Preferred Stock	⁽¹⁾	02/06/2026		C⁽¹⁾			28,229	⁽¹⁾	⁽¹⁾	Common Stock	3,785	⁽¹⁾	0	I	By The Column Group IV-A, LP⁽³⁾
Series D Preferred Stock	⁽¹⁾	02/06/2026		C⁽¹⁾			5,133,076	⁽¹⁾	⁽¹⁾	Common Stock	688,283	⁽¹⁾	0	I	By The Column Group Opportunity III, LP⁽⁴⁾

1. Name and Address of Reporting Person^*

Column Group IV GP, LP

(Last)

(First)

(Middle)

1 LETTERMAN DR., BLDG D, SUITE DM-900

(Street)

SAN FRANCISCO

94129

(City)

(State)

(Zip)

Relationship of Reporting Person(s) to Issuer

Director	X	10% Owner
Officer (give title below)		Other (specify below)

1. Name and Address of Reporting Person^*

Column Group IV-A, LP

(Last)

(First)

(Middle)

1 LETTERMAN DR., BLDG D, SUITE DM-900

(Street)

SAN FRANCISCO

94129

(City)

(State)

(Zip)

Relationship of Reporting Person(s) to Issuer

Director	X	10% Owner
Officer (give title below)		Other (specify below)

1. Name and Address of Reporting Person^*

Column Group IV, LP

(Last)

(First)

(Middle)

1 LETTERMAN DR., BLDG D, SUITE DM-900

(Street)

SAN FRANCISCO

94129

(City)

(State)

(Zip)

Relationship of Reporting Person(s) to Issuer

Director	X	10% Owner
Officer (give title below)		Other (specify below)

1. Name and Address of Reporting Person^*

Column Group Opportunity III, LP

(Last)

(First)

(Middle)

1 LETTERMAN DR., BLDG D, SUITE DM-900

(Street)

SAN FRANCISCO

94129

(City)

(State)

(Zip)

Relationship of Reporting Person(s) to Issuer

Director	X	10% Owner
Officer (give title below)		Other (specify below)

1. Name and Address of Reporting Person^*

Column Group Opportunity III GP, LP

(Last)

(First)

(Middle)

1 LETTERMAN DR., BLDG D, SUITE DM-900

(Street)

SAN FRANCISCO

94129

(City)

(State)

(Zip)

Relationship of Reporting Person(s) to Issuer

Director	X	10% Owner
Officer (give title below)		Other (specify below)

1. Name and Address of Reporting Person^*

TCG Opportunity III GP, LLC

(Last)

(First)

(Middle)

1 LETTERMAN DR., BLDG D, SUITE DM-900

(Street)

SAN FRANCISCO

94129

(City)

(State)

(Zip)

Relationship of Reporting Person(s) to Issuer

Director	X	10% Owner
Officer (give title below)		Other (specify below)

1. Name and Address of Reporting Person^*

Kutzkey Tim

(Last)

(First)

(Middle)

1 LETTERMAN DR., BLDG D, SUITE DM-900

(Street)

SAN FRANCISCO

94129

(City)

(State)

(Zip)

Relationship of Reporting Person(s) to Issuer

Director	X	10% Owner
Officer (give title below)		Other (specify below)

1. Name and Address of Reporting Person^*

Svennilson Peter

(Last)

(First)

(Middle)

1 LETTERMAN DR., BLDG D, SUITE DM-900

(Street)

SAN FRANCISCO

94129

(City)

(State)

(Zip)

Relationship of Reporting Person(s) to Issuer

Director	X	10% Owner
Officer (give title below)		Other (specify below)

Explanation of Responses:

1. Immediately prior to the closing of the Issuer's initial public offering of its Common Stock, each share of Series A Preferred Stock, Series A-1 Preferred Stock, Series B-1 Preferred Stock, Series C Preferred Stock, Series C-1 Preferred Stock and Series D Preferred Stock automatically converted into approximately 0.1340878 shares of the Issuer's Common Stock and has no expiration date

2. The shares are directly held by The Column Group IV, LP ("TCG IV LP"). The Column Group IV GP, LP ("TCG IV GP LP") is the general partner of TCG IV LP and may be deemed to have voting and investment power with respect to shares directly held by TCG IV LP. Peter Svennilson and Tim Kutzkey are the managing partners of TCG IV GP LP and may each be deemed to share voting, investment and dispositive power with respect to securities directly held by TCG IV LP. Each of the Reporting Persons disclaims beneficial ownership of the securities noted herein, except to the extent of its or his pecuniary interest therein.

3. The shares are directly held by The Column Group IV-A, LP ("TCG IV-A LP"). TCG IV GP LP is the general partner of the TCG IV-A LP and may be deemed to have voting and investment power with respect to shares directly held by the Reporting Person. Peter Svennilson and Tim Kutzkey are the managing partners of TCG IV GP LP and may each be deemed to share voting, investment and dispositive power with respect to securities directly held by TCG IV-A LP. Each of the Reporting Persons disclaims beneficial ownership of the securities noted herein, except to the extent of its or his pecuniary interest therein.

4. The securities are directly held by The Column Group Opportunity III, LP ("TCG Opportunity III LP"). The Column Group Opportunity III GP, LP ("TCG Opportunity III GP LP") is the general partner of TCG Opportunity III LP. TCG Opportunity III GP, LLC is the general partner of TCG Opportunity III GP LP and the ultimate general partner of TCG Opportunity III LP. Each of TCG Opportunity III GP LP and TCG Opportunity III GP, LLC may be deemed to have voting, investment and dispositive power with respect to securities directly held by TCG Opportunity III LP. Peter Svennilson and Tim Kutzkey are the managing members of TCG Opportunity III GP, LLC and may each be deemed to share voting, investment and dispositive power with respect to securities directly held by TCG Opportunity III LP. Each of the Reporting Persons disclaims beneficial ownership of the securities noted herein, except to the extent of its or his pecuniary interest therein.

	/s/ The Column Group IV GP, LP, /s/ James Evangelista, Attorney-in-Fact	02/09/2026
	/s/ The Column Group IV-A, LP. by The Column Group IV GP, LP, its general partner, /s/ James Evangelista, Attorney-in-Fact	02/09/2026
	/s/ The Column Group IV, LP by The Column Group IV GP, LP, its general partner /s/ James Evangelista, Attorney-in-Fact	02/09/2026
	/s/ The Column Group Opportunity III, LP, by The Column Group Opportunity GP, LP its general partner, by TCG Opportunity III GP, LLC, its general partner, /s/ James Evangelista, Attorney-in-Fact	02/09/2026
	/s/ The Column Group Opportunity III GP, LP., by TCG Opportunity III GP, LLC, its general partner, /s/ James Evangelista, Attorney-in-Fact	02/09/2026
	/s/ TCG Opportunity III GP, LLC, /s/ James Evangelista, Attorney-in-Fact	02/09/2026
	/s/James Evangelista, as attorney-in-fact for Tim Kutzkey	02/09/2026
	/s/James Evangelista, as attorney-in-fact for Peter Svennilson	02/09/2026
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
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