| 
               
                Proposal 
               
             | 
             |  | 
               
                Vote Required 
               
             | 
             | 
| Re-election of the Class III Directors |  |  | Plurality of the votes cast (the director receiving the most “FOR” votes) |  | 
| Ratification of the Appointment of Mayer Hoffman McCann P.C. as our Independent Registered Public Accounting Firm for our Fiscal Year Ending December 31, 2021 |  |  | A majority of the votes entitled to vote thereon and present at the Annual Meeting |  | 
| 
               
                Name 
               
             | 
             |  | 
               
                Age 
               
             | 
             |  | 
               
                Position(s) 
               
             | 
             | 
| Eric Patzer, Ph.D. |  |  | 
               
                72 
               
             | 
             |  | Executive Chairman of the Board of Directors, Class III Director |  | 
| Vu Truong, Ph.D. |  |  | 
               
                57 
               
             | 
             |  | 
               
                Chief Executive Officer, Chief Scientific Officer and Class III Director
               
             | 
             | 
| 
               
                Name 
               
             | 
             |  | 
               
                Age 
               
             | 
             |  | 
               
                Position(s) 
               
             | 
             | 
| Craig Gibbs, Ph.D. |  |  | 
               
                58 
               
             | 
             |  | Class I Director |  | 
| John Hamilton |  |  | 
               
                76 
               
             | 
             |  | Class I Director |  | 
| Robert R. Ruffolo, Ph.D. |  |  | 
               
                71 
               
             | 
             |  | Class I Director |  | 
| Susan Windham-Bannister, Ph.D. |  |  | 
               
                69 
               
             | 
             |  | Class II Director Nominee |  | 
| 
               
                Name 
               
             | 
             |  | 
               
                Age 
               
             | 
             |  | 
               
                Position(s) 
               
             | 
             | 
| Eric Patzer, Ph.D. |  |  | 
               
                72 
               
             | 
             |  | Executive Chairman of the Board of Directors |  | 
| Vu Truong, Ph.D. |  |  | 
               
                57 
               
             | 
             |  | Chief Executive Officer, Chief Scientific Officer and Director |  | 
| Michael A. Nazak |  |  | 
               
                62 
               
             | 
             |  | Chief Financial Officer |  | 
| 
               
                Dr. Hasan Jafri, M.D.
               
             | 
             |  | 
               
                54 
               
             | 
             |  | Chief Medical Officer |  | 
| 
               
                Name and Principal Position 
               
             | 
             |  | 
               
                Year 
               
             | 
             |  | 
               
                Salary ($) 
               
             | 
             |  | 
               
                Bonus ($) 
               
             | 
             |  | 
               
                Option
                 
            Awards ($)(1)  | 
             |  | 
               
                Total ($) 
               
             | 
             | |||||||||||||||
| 
               
                Vu Truong, Ph.D.
                 
            Chief Executive Officer and Chief Scientific Officer  | 
             |  |  |  | 2020 |  |  |  |  |  | 475,000 |  |  |  |  |  | 91,125 |  |  |  |  |  | 217,367 |  |  |  |  |  | 783,492 |  |  | 
|  |  |  | 2019 |  |  |  |  |  | 450,000 |  |  |  |  |  | 202,500 |  |  |  |  |  | 1,217,142 |  |  |  |  |  | 1,869,642 |  |  | ||
| 
               
                Michael A. Nazak(2)
                 
            Chief Financial Officer  | 
             |  |  |  | 2020 |  |  |  |  |  | 315,000 |  |  |  |  |  | — |  |  |  |  |  | 65,166 |  |  |  |  |  | 380,166 |  |  | 
| 
               
                Hasan Jafri, M.D.(3)
                 
            Chief Medical Officer  | 
             |  |  |  | 2020 |  |  |  |  |  | 223,660 |  |  |  |  |  | — |  |  |  |  |  | 407,242 |  |  |  |  |  | 630,902 |  |  | 
|  |  |  | 
               
                Option Awards 
               
             | 
             |  |  |  |  |  |  |  |  |  | |||||||||||||||||||||
|  |  |  | 
               
                Number of
                 
            Securities Underlying Unexercised Options: Exercisable (#)  | 
             |  | 
               
                Number of
                 
            Securities Underlying Unexercised Options: Unexercisable (#)  | 
             |  | 
               
                Option
                 
            Exercise Price ($)  | 
             |  | 
               
                Option
                 
            Expiration Date  | 
             |  |  |  | ||||||||||||||||||
| 
               
                Dr. Vu Truong 
               
             | 
             |  |  |  | 77,908 |  |  |  |  |  | — |  |  |  |  |  | 2.89 |  |  |  |  |  | 3/6/2025(1) |  |  |  |  |  | ||||||
|  |  |  |  |  | 23,373 |  |  |  |  |  | — |  |  |  |  |  | 12.96 |  |  |  |  |  | 12/4/2025(2) |  |  |  |  |  | ||||||
|  |  |  |  |  | 77,908 |  |  |  |  |  | — |  |  |  |  |  | 13.16 |  |  |  |  |  | 10/20/2026(3) |  |  |  |  |  | ||||||
|  |  |  |  |  | 87,646 |  |  |  |  |  | 29,215 |  |  |  |  |  | 17.01 |  |  |  |  |  | 1/26/2028(4) |  |  |  |  |  | ||||||
|  |  |  |  |  | 91,667 |  |  |  |  |  | 108,333 |  |  |  |  |  | 8.20 |  |  |  |  |  | 2/21/2029(5) |  |  |  |  |  | ||||||
|  |  |  |  |  | 33,334 |  |  |  |  |  | 16,666 |  |  |  |  |  | 5.24 |  |  |  |  |  | 4/3/2030(6) |  |  |  |  |  | ||||||
| 
               
                Michael A. Nazak 
               
             | 
             |  |  |  | 20,834 |  |  |  |  |  | 19,166 |  |  |  |  |  | 8.50 |  |  |  |  |  | 12/5/2028(7) |  |  |  |  |  | ||||||
|  |  |  |  |  | 4,584 |  |  |  |  |  | 15,416 |  |  |  |  |  | 4.45 |  |  |  |  |  | 1/2/2030(8) |  |  |  |  |  | ||||||
| 
               
                Hasan Jafri, M.D. 
               
             | 
             |  |  |  | — |  |  |  |  |  | 80,000 |  |  |  |  |  | 6.16 |  |  |  |  |  | 6/25/2030(9) |  |  |  |  |  | ||||||
| 
               
                Name 
               
             | 
             |  | 
               
                Director
                 
            Fees ($)  | 
             |  | 
               
                Total ($) 
               
             | 
             | ||||||
| 
               
                Craig Gibbs, Ph.D. 
               
             | 
             |  |  |  | 26,000 |  |  |  |  |  | 26,000 |  |  | 
| 
               
                John Hamilton 
               
             | 
             |  |  |  | 31,000 |  |  |  |  |  | 31,000 |  |  | 
| 
               
                Robert R. Ruffolo, Ph.D. 
               
             | 
             |  |  |  | 23,000 |  |  |  |  |  | 23,000 |  |  | 
| 
               
                Susan Windham-Bannister, Ph.D.
               
             | 
             |  |  |  | 28,000 |  |  |  |  |  | 28,000 |  |  | 
| 
               
                Beneficial Owner 
               
             | 
             |  | 
               
                Number of Shares
                 
            Beneficially Owned  | 
             |  | 
               
                Percentage of
                 
            Common Stock Beneficially Owned  | 
             | ||||||
| Directors and Executive Officers |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 
               
                Dr. Eric Patzer(1)
               
             | 
             |  |  |  | 810,573 |  |  |  |  |  | 7.1 |  |  | 
| 
               
                Dr. Vu Truong(2)
               
             | 
             |  |  |  | 1,176,296 |  |  |  |  |  | 10.1 |  |  | 
| 
               
                Michael A. Nazak(3)
               
             | 
             |  |  |  | 33,751 |  |  |  |  |  | * |  |  | 
| 
               
                Dr. Hasan Jafri(3)
               
             | 
             |  |  |  | 20,417 |  |  |  |  |  | * |  |  | 
| 
               
                Craig Gibbs(3)
               
             | 
             |  |  |  | 38,529 |  |  |  |  |  | * |  |  | 
| 
               
                John Hamilton(3)
               
             | 
             |  |  |  | 38,529 |  |  |  |  |  | * |  |  | 
| 
               
                Robert Ruffolo(3)
               
             | 
             |  |  |  | 29,180 |  |  |  |  |  | * |  |  | 
| 
               
                Susan Windham-Bannister(3)
               
             | 
             |  |  |  | 23,334 |  |  |  |  |  | * |  |  | 
| 
               
                All directors and officers as a group (8 persons)(4)
               
             | 
             |  |  |  | 2,170,609 |  |  |  |  |  | 18.1 |  |  | 
| Five Percent Stockholders |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| 
               
                Hepalink USA, Inc.(5)
               
             | 
             |  |  |  | 1,087,476 |  |  |  |  |  | 9.5 |  |  | 
| 
               
                Serum International B.V. 
               
             | 
             |  |  |  | 801,820 |  |  |  |  |  | 7.1 |  |  | 
| 
               
                Francis Capital Management LLC(6)
               
             | 
             |  |  |  | 676,859 |  |  |  |  |  | 6.0 |  |  | 
| 
               
                Healthcare Industry (Cayman) A Co., Limited(7)
               
             | 
             |  |  |  | 653,105 |  |  |  |  |  | 5.8 |  |  | 
|  |  |  | 
               
                2020 
               
             | 
             |  | 
               
                2019 
               
             | 
             | ||||||
| 
               
                Audit Fees 
               
             | 
             |  |  | $ | 257,430 |  |  |  |  | $ | 357,069 |  |  | 
| 
               
                Audit Related Fees 
               
             | 
             |  |  | $ | — |  |  |  |  | $ | — |  |  | 
| 
               
                Tax Fees 
               
             | 
             |  |  | $ | — |  |  |  |  | $ | — |  |  | 
| 
               
                Other Fees 
               
             | 
             |  |  | $ | — |  |  |  |  | $ | — |  |  | 
| 
               
                Totals 
               
             | 
             |  |  | $ | 257,430 |  |  |  |  | $ | 357,069 |  |  | 
|  | 1. Election of Director Nominee |  |  | 
               
                FOR
               
             | 
             |  | 
               
                WITHHOLD
               
             | 
             | 
|  | 
               
                01 – Eric Patzer, Ph.D. 
               
             | 
             |  | 
               
                ☐ 
               
             | 
             |  | 
               
                ☐ 
               
             | 
             | 
|  | 
               
                02 – Vu Truong, Ph.D. 
               
             | 
             |  | 
               
                ☐ 
               
             | 
             |  | 
               
                ☐
               
             | 
             | 
|  | 
               
                2. Proposal to ratify Mayer Hoffman McCann P.C. as the Company’s independent registered public accountants for fiscal year ending December 31, 2021. 
               
             | 
             |  | 
               
                FOR
               
             | 
             |  | 
               
                AGAINST
               
             | 
             |  | 
               
                ABSTAIN
               
             | 
             | 
|  | 
               
                ☐ 
               
             | 
             |  | 
               
                ☐ 
               
             | 
             |  | 
               
                ☐
               
             | 
             |