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Check the appropriate box to designate the rule pursuant to which this Schedule is filed:
Checkbox not checked   Rule 13d-1(b)
Checkbox checked   Rule 13d-1(c)
Checkbox not checked   Rule 13d-1(d)






SCHEDULE 13G




Comment for Type of Reporting Person:  The figures in Items 6, 8, and 9 include (i) 4,325,185 shares of common stock, $0.0001 par value per share ("Common Stock") of Shattuck Labs, Inc. (the "Issuer") owned by the Reporting Persons; and (ii) 2,218,055 shares of Common Stock that may be acquired by the Reporting Persons within 60 days, subject to the Beneficial Ownership Limitation (as defined hereafter), upon the exercise of certain pre-funded warrants and common warrants (the "Warrants") held by the Reporting Persons. Pursuant to the terms of the Warrants, the Issuer may not effect any exercise of the Warrants, and a holder may not exercise any Warrants, to the extent that after giving effect to such issuance after exercise, the aggregate number of shares of Common Stock then beneficially owned by the Reporting Persons would exceed 9.99% of the outstanding shares of Common Stock (the "Beneficial Ownership Limitation"). The figure in Item 11 is based upon (i) 2,218,055 shares of Common Stock that may be acquired by the Reporting Persons within 60 days upon the conversion of the Warrants up to the Beneficial Ownership Limitation; and (ii) 63,279,843 shares of Common Stock outstanding as of October 23, 2025, as disclosed in the Issuer's quarterly report on Form 10-Q for the quarterly period ended September 30, 2025, filed with the U.S. Securities and Exchange Commission (the "SEC") on November 6, 2025.


SCHEDULE 13G




Comment for Type of Reporting Person:  The figures in Items 6, 8, and 9 include (i) 398,022 shares of Common Stock of the Issuer owned by Prosight Fund; and (ii) 202,288 shares of Common Stock that may be acquired by Prosight Fund within 60 days, subject to the Beneficial Ownership Limitation, upon the exercise of the Warrants held by the Prosight Fund. The figure in Item 11 is based upon (i) 202,288 shares of Common Stock that may be acquired by the Reporting Persons within 60 days upon the conversion of the Warrants up to the Beneficial Ownership Limitation; and (ii) 63,279,843 shares of Common Stock outstanding as of October 23, 2025, as disclosed in the Issuer's quarterly report on Form 10-Q for the quarterly period ended September 30, 2025, filed with the SEC on November 6, 2025.


SCHEDULE 13G




Comment for Type of Reporting Person:  The figures in Items 6, 8, and 9 include (i) 1,192,668 shares of Common Stock of the Issuer owned by Prosight Plus Fund; and (ii) 1,934,514 shares of Common Stock that may be acquired by Prosight Plus Fund within 60 days, subject to the Beneficial Ownership Limitation, upon the exercise of the Warrants held by the Prosight Plus Fund. The figure in Item 11 is based upon (i) 1,934,514 shares of Common Stock that may be acquired by the Reporting Persons within 60 days upon the conversion of the Warrants up to the Beneficial Ownership Limitation; and (ii) 63,279,843 shares of Common Stock outstanding as of October 23, 2025, as disclosed in the Issuer's quarterly report on Form 10-Q for the quarterly period ended September 30, 2025, filed with the SEC on November 6, 2025.


SCHEDULE 13G




Comment for Type of Reporting Person:  The figures in Items 6, 8, and 9 include (i) 4,325,185 shares of Common Stock of the Issuer owned by the Reporting Persons; and (ii) 2,218,055 shares of Common Stock that may be acquired by the Reporting Persons within 60 days, subject to the Beneficial Ownership Limitation, upon the exercise of the Warrants held by the Reporting Persons. The figure in Item 11 is based upon (i) 2,218,055 shares of Common Stock that may be acquired by the Reporting Persons within 60 days upon the conversion of the Warrants up to the Beneficial Ownership Limitation; and (ii) 63,279,843 shares of Common Stock outstanding as of October 23, 2025, as disclosed in the Issuer's quarterly report on Form 10-Q for the quarterly period ended September 30, 2025, filed with the SEC on November 6, 2025.


SCHEDULE 13G




Comment for Type of Reporting Person:  The figures in Items 6, 8, and 9 include (i) 4,325,185 shares of Common Stock of the Issuer owned by the Reporting Persons; and (ii) 2,218,055 shares of Common Stock that may be acquired by the Reporting Persons within 60 days, subject to the Beneficial Ownership Limitation, upon the exercise of the Warrants held by the Reporting Persons. The figure in Item 11 is based upon (i) 2,218,055 shares of Common Stock that may be acquired by the Reporting Persons within 60 days upon the conversion of the Warrants up to the Beneficial Ownership Limitation; and (ii) 63,279,843 shares of Common Stock outstanding as of October 23, 2025, as disclosed in the Issuer's quarterly report on Form 10-Q for the quarterly period ended September 30, 2025, filed with the SEC on November 6, 2025.


SCHEDULE 13G



 
Prosight Management, LP
 
Signature:Prosight Partners, LLC
Name/Title:General Partner
Date:11/13/2025
 
Signature:/s/ W. Lawrence Hawkins
Name/Title:Sole Manager of the General Partner
Date:11/13/2025
 
Prosight Fund, LP
 
Signature:Prosight Management, LP
Name/Title:General Partner
Date:11/13/2025
 
Signature:Prosight Partners, LLC
Name/Title:Sole Manager of the General Partner
Date:11/13/2025
 
Signature:/s/ W. Lawrence Hawkins
Name/Title:Sole Manager of the General Partner of the General Partner
Date:11/13/2025
 
Prosight Plus Fund, LP
 
Signature:Prosight Management, LP
Name/Title:General Partner
Date:11/13/2025
 
Signature:Prosight Partners, LLC
Name/Title:General Partner of the General Partner
Date:11/13/2025
 
Signature:/s/ W. Lawrence Hawkins
Name/Title:Sole Manager of the General Partner of the General Partner
Date:11/13/2025
 
Prosight Partners, LLC
 
Signature:/s/ W. Lawrence Hawkins
Name/Title:Sole Manager
Date:11/13/2025
 
W. Lawrence Hawkins
 
Signature:/s/ W. Lawrence Hawkins
Name/Title:W. Lawrence Hawkins
Date:11/13/2025
Exhibit Information

Exhibit 99.1: Joint Filing Agreement (incorporated herein by reference to Exhibit 99.1 to the Schedule 13G filed on December 29, 2023, by the Reporting Persons with the SEC).