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                          September 28, 2022

       Saundra Pelletier
       Chief Executive Officer
       Evofem Biosciences, Inc.
       12400 High Bluff Drive, Suite 600
       San Diego, CA 92130

                                                        Re: Evofem Biosciences,
Inc.
                                                            Registration
Statement on Form S-1
                                                            Filed September 23,
2022
                                                            File No. 333-267591

       Dear Ms. Pelletier:

              This is to advise you that we have not reviewed and will not
review your registration
       statement.

               Please refer to Rules 460 and 461 regarding requests for
acceleration. We remind you
       that the company and its management are responsible for the accuracy and
adequacy of their
       disclosures, notwithstanding any review, comments, action or absence of
action by the staff.

                                                        Please contact Jason
Drory at 202-551-8342 with any questions.




                          Sincerely,


                          Division of Corporation Finance

                          Office of Life Sciences
       cc:                                              Melanie Levy