Exhibit 15.1
Consent of Independent Registered Public Accounting Firm
We consent to the incorporation by reference in the following Registration Statements:
| (1) | Registration Statement (Form F-3 No. 333-222848) of Pyxis Tankers Inc., and |
| (2) | Registration Statement (Form F-3 No. 333-222160) of Pyxis Tankers Inc. |
of our report dated March 31, 2020, with respect to the consolidated financial statements and the financial statement schedule of Pyxis Tankers Inc. included in this Annual Report (Form 20-F) of Pyxis Tankers Inc. for the year ended December 31, 2019.
/s/ Ernst & Young (Hellas) Certified Auditors Accountants S.A.
Athens, Greece
March 31, 2020