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S-4 S-4/A EX-FILING FEES 333-281324 0001651308 BeiGene, Ltd. 0001651308 2025-02-27 2025-02-27 0001651308 1 2025-02-27 2025-02-27 0001651308 2 2025-02-27 2025-02-27 0001651308 3 2025-02-27 2025-02-27 iso4217:USD xbrli:pure xbrli:shares

Calculation of Filing Fee Tables

S-4

BeiGene, Ltd.

Table 1: Newly Registered and Carry Forward Securities

Security Type

Security Class Title

Fee Calculation or Carry Forward Rule

Amount Registered

Proposed Maximum Offering Price Per Unit

Maximum Aggregate Offering Price

Fee Rate

Amount of Registration Fee

Carry Forward Form Type

Carry Forward File Number

Carry Forward Initial Effective Date

Filing Fee Previously Paid in Connection with Unsold Securities to be Carried Forward

Newly Registered Securities
Fees to be Paid 1 Equity Ordinary Shares, par value US$0.0001 per share Other 20,751,796 $ 18.6123 $ 386,238,652.69 0.0001531 $ 59,133.14
Fees Previously Paid 2 Equity Ordinary Shares, par value US$0.0001 per share Other 7,838,441 $ 13.8224 $ 108,346,066.88 $ 16,587.78
Fees Previously Paid 3 Equity Ordinary Shares, par value US$0.0001 per share Other 1,379,529,263 $ 12.3342 $ 17,015,389,835.69 $ 2,511,471.54
Carry Forward Securities
Carry Forward Securities

Total Offering Amounts:

$ 17,509,974,555.26

$ 2,587,192.46

Total Fees Previously Paid:

$ 2,528,059.32

Total Fee Offsets:

$ 0.00

Net Fee Due:

$ 59,133.14

Offering Note

1

The Registrant intends to change its jurisdiction of incorporation from the Cayman Islands to Switzerland through a transaction known as a continuation under Section 206 of the Companies Act (as amended) of the Cayman Islands and Article 161 of the Swiss Federal Code on Private International Law (the "Continuation"). All securities being registered will be securities of the continuing entity following the effectiveness of the Continuation. Includes the Ordinary Shares of the Registrant into which all Ordinary Shares of the Registrant that are issued and outstanding (including a total of 1,393,867,704 Ordinary Shares of the Registrant issued and outstanding as of February 20, 2025 and 14,251,796 Ordinary Shares to be issued upon the potential exercise, if any, of the outstanding equity awards of the Registrant between February 20, 2025 and the estimated closing date of the Continuation, based on the Registrant's reasonable good faith estimate) immediately prior to the effectiveness of the Continuation will automatically be converted by operation of law upon the effectiveness of the Continuation. Certain Ordinary Shares may be represented by the Registrant's American Depositary Shares ("ADSs"). Each ADS represents 13 Ordinary Shares. ADSs issuable upon deposit of the Ordinary Shares registered hereby will be registered pursuant to a separate Registration Statement on Form F-6. Pursuant to Rule 416(a) under the Securities Act of 1933, as amended (the "Securities Act"), this Registration Statement shall also cover any additional Ordinary Shares of the Registrant which become issuable in respect of the securities identified in the above table by reason of any stock dividend, stock split, recapitalization or other similar transaction effected without the receipt of consideration that increases the number of the Registrant's outstanding Ordinary Shares. The Registrant previously paid a registration fee of $2,528,059.32 in connection with the initial filing of this Registration Statement to register 1,387,367,704 Ordinary Shares. The Registrant is paying an additional registration fee in the amount of $59,133.14 in connection with the filing of this Amendment No. 2 to the Registration Statement to reflect the addition of 20,751,796 additional Ordinary Shares in accordance with Rule 457(c). The registration fee to be paid is estimated in accordance with Rule 457(f)(1) of the Securities Act, solely for the purpose of calculating the registration fee on basis of US$241.96, the average of the high (US$246.80) and low (US$237.12) prices of the Registrant's ADSs, as quoted on the Nasdaq Global Select Market on February 20, 2025 (a date within five business days prior to the filing of this Amendment No. 2 to this Registration Statement), divided by 13, the then Ordinary Share-to-ADS ratio.

2

See offering in note 1

3

See offering in note 1.