| | | | | | | | | | | | | | |
| Name of Subsidiary | | Jurisdiction of Incorporation or Organization | | Percentage of Ownership by the Registrant |
| BeiGene 101 | | Cayman Islands | | 100 | % |
| BeOne Medicines Argentina S.R.L | | Argentina | | 100 | % |
| BeOne Medicines AUS PTY LTD | | Australia | | 100 | % |
| BeOne Medicines Austria GmbH | | Austria | | 100 | % |
| BeOne Medicines (Beijing) Co., Ltd. | | People’s Republic of China | | 100 | % |
| BeOne Medicines Belgium SRL | | Belgium | | 100 | % |
| BeOne Biologics Co., Ltd. | | People’s Republic of China | | 100 | % |
| BeOne Medicines Brasil Ltda. | | Brazil | | 100 | % |
| BeOne Medicines (Canada) ULC | | Canada | | 100 | % |
| BeOne Medicines Chile Limitada | | Chile | | 100 | % |
| BeOne Medicines Colombia S.A.S. | | Colombia | | 100 | % |
| BeOne Medicines ESP, S.L.U. (Spain) | | Spain | | 100 | % |
| BeOne Medicines France Sarl | | France | | 100 | % |
| BeOne Medicines Germany GmbH | | Germany | | 100 | % |
| BeOne Guangzhou Biologics Manufacturing Co., Ltd. | | People’s Republic of China | | 100 | % |
| BeOne (Guangzhou) Innovation Technology Co., Ltd. | | People’s Republic of China | | 100 | % |
| BeOne Medicines (Hong Kong) Co., Limited | | Hong Kong | | 100 | % |
| BeOne Medicines Hopewell Urban Renewal, LLC | | New Jersey, United States | | 100 | % |
| BeOne Medicines International GmbH | | Switzerland | | 100 | % |
| BeOne Medicines Ireland Limited | | Republic of Ireland | | 100 | % |
| BeOne Medicines Italy S.r.l. | | Italy | | 100 | % |
| BeOne Medicines Japan | | Japan | | 100 | % |
| BeOne Medicines Korea Y.H. | | South Korea | | 100 | % |
| BeOne Medicines Malaysia Sdn Bhd. | | Malaysia | | 100 | % |
| BeOne Medicines Mexico S. de R.L. de C.V. | | Mexico | | 100 | % |
| BeOne Medicines Netherlands B.V. | | Netherlands | | 100 | % |
| BeOne Medicines NZ Unlimited | | New Zealand | | 100 | % |
| BeOne Medicines Peru (Sociedad Comercial de Responsabilidad Limitada - S.R.L) | | Peru | | 100 | % |
| BeOne Medicines Pharmaceuticals GmbH | | Switzerland | | 100 | % |
| BeOne Pharmaceutical (Guangzhou) Co., Ltd. | | People’s Republic of China | | 100 | % |
| BeOne Medicines Israel Ltd. | | Israel | | 100 | % |
| BeOne Pharmaceutical (Shanghai) Co., Ltd. | | People’s Republic of China | | 100 | % |
| BeOne Medicines Poland sp. z o.o. | | Poland | | 100 | % |
| BeOne Medicines Portugal, Unipessoal Lda | | Portugal | | 100 | % |
| BeiGene Shanghai | | Cayman Islands | | 100 | % |
| BeiGene Shanghai 101 | | Cayman Islands | | 100 | % |
| BeOne Medicines (Shanghai) Co., Ltd. | | People’s Republic of China | | 100 | % |
| BeOne Medicines (Shanghai) Development Co., Ltd. | | People’s Republic of China | | 100 | % |
| BeOne Medicines (Shanghai) Management Consulting Co., Ltd. | | People’s Republic of China | | 100 | % |
| BeOne Medicines (Shanghai) Research & Development Co., Ltd. | | People’s Republic of China | | 100 | % |
| BeOne Medicines Shanghai Asset Limited | | Hong Kong | | 100 | % |
| BeOne Medicines Singapore Pte. Ltd | | Singapore | | 100 | % |
| BeOne Medicines South Africa (PTY) Ltd. | | South Africa | | 100 | % |
| BeOne Pharmaceutical (Suzhou) Co., Ltd. | | People’s Republic of China | | 100 | % |