Exhibit 21.1

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Tabula Rasa HealthCare, Inc. Subsidiaries

The following are the Company’s subsidiaries as of December 31, 2021 and the states or jurisdictions in which they are organized; provided, however, the names of particular subsidiaries have been omitted because, considered in the aggregate as a single subsidiary, they would not constitute, as of December 31, 2021, a “significant subsidiary” as that term is defined in Rule 1-02(w) of Regulation S-X under the Securities Exchange Act of 1934, as amended.

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