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S-3 S-3 EX-FILING FEES 0001653087 Alector, Inc. N/A N/A 0.0001381 0.0001381 0.0001381 0.0001381 0.0001381 0.0001381 0001653087 2026-03-12 2026-03-12 0001653087 1 2026-03-12 2026-03-12 0001653087 2 2026-03-12 2026-03-12 0001653087 3 2026-03-12 2026-03-12 0001653087 4 2026-03-12 2026-03-12 0001653087 5 2026-03-12 2026-03-12 0001653087 6 2026-03-12 2026-03-12 0001653087 7 2026-03-12 2026-03-12 0001653087 8 2026-03-12 2026-03-12 0001653087 9 2026-03-12 2026-03-12 0001653087 10 2026-03-12 2026-03-12 0001653087 11 2026-03-12 2026-03-12 0001653087 12 2026-03-12 2026-03-12 0001653087 13 2026-03-12 2026-03-12 0001653087 14 2026-03-12 2026-03-12 iso4217:USD xbrli:pure xbrli:shares

Calculation of Filing Fee Tables

S-3

Alector, Inc.

Table 1: Newly Registered and Carry Forward Securities ☐Not Applicable

Security Type

Security Class Title

Fee Calculation or Carry Forward Rule

Amount Registered

Proposed Maximum Offering Price Per Unit

Maximum Aggregate Offering Price

Fee Rate

Amount of Registration Fee

Carry Forward Form Type

Carry Forward File Number

Carry Forward Initial Effective Date

Filing Fee Previously Paid in Connection with Unsold Securities to be Carried Forward

Newly Registered Securities
Equity Common Stock, $0.0001 par value per share 457(o)
Equity Preferred Stock, $0.0001 par value per share 457(o)
Debt Debt Securities 457(o)
Other Warrants 457(o)
Other Purchase Contracts 457(o)
Other Units 457(o)
Fees to be Paid 1 Unallocated (Universal) Shelf 457(o) $ 91,803,316.86 0.0001381 $ 12,678.04
Fees Previously Paid
Carry Forward Securities
Carry Forward Securities Equity Common Stock, $0.0001 par value per share 415(a)(6) S-3 333-270126 05/01/2023
Carry Forward Securities Equity Preferred Stock, $0.0001 par value per share 415(a)(6) S-3 333-270126 05/01/2023
Carry Forward Securities Debt Debt Securities 415(a)(6) S-3 333-270126 05/01/2023
Carry Forward Securities Other Warrants 415(a)(6) S-3 333-270126 05/01/2023
Carry Forward Securities Other Purchase Contracts 415(a)(6) S-3 333-270126 05/01/2023
Carry Forward Securities Other Units 415(a)(6) S-3 333-270126 05/01/2023
Carry Forward Securities 2 Unallocated (Universal) Shelf 415(a)(6) $ 308,196,683.14 S-3 333-270126 05/01/2023 $ 18,961.80

Total Offering Amounts:

$ 400,000,000.00

$ 12,678.04

Total Fees Previously Paid:

$ 0.00

Total Fee Offsets:

$ 0.00

Net Fee Due:

$ 12,678.04

Offering Note

1

There are being registered hereunder such indeterminate number of (a) shares of common stock, (b) shares of preferred stock, (c) debt securities, (d) warrants to purchase common stock or preferred stock, (e) purchase contracts, and (f) units consisting of some or all of these securities in any combination, to be sold by the registrant from time to time at unspecified prices which shall have an aggregate initial offering price not to exceed $400,000,000. There are also being registered hereunder an indeterminate number of shares of common stock and preferred stock as shall be issuable upon conversion, exchange or exercise of any securities that provide for such issuance. Pursuant to Rule 416 under the Securities Act of 1933, as amended (the Securities Act), the shares being registered hereunder include such indeterminate number of shares of the registrant's securities as may be issuable with respect to the shares being registered hereunder as a result of stock splits, stock dividends or similar transactions. The proposed maximum per security and aggregate offering prices will be determined, from time to time, by the registrant in connection with the issuance by the registrant of the securities registered hereunder and is not specified as to each class of security pursuant to Instruction 2.A.iii.b. to the Calculation of Filing Fee Tables and Related Disclosure on Item 16(b) of Form S-3 under the Securities Act.

2

Pursuant to Rule 415(a)(6) under the Securities Act, the securities registered pursuant to this registration statement represent $308,196,683.14 of unsold securities (the Unsold Securities) previously registered pursuant to a registration statement on Form S-3 (File No. 333-270126), initially filed by the registrant with the Securities and Exchange Commission on February 28, 2023 and declared effective on May 1, 2023 (the Prior Registration Statement). The Prior Registration Statement registered securities for a maximum aggregate offering price of $400,000,000, and of that amount the registrant has previously sold securities for an aggregate offering price of $91,803,316.86, leaving a balance of unsold securities with an aggregate offering price of $308,196,683.14. In connection with the filing of the Prior Registration Statement, the Registrant paid a filing fee of $24,610 associated with the offering of the Unsold Securities (based on the filing fee rate in effect at the time of the filing of the Prior Registration Statement), calculated in accordance with Rule 457(o) under the Securities Act. Of this amount, $18,961.80 is associated with the Unsold Securities. The registrant may continue to offer and sell under the Prior Registration Statement the Unsold Securities being registered hereunder. To the extent that, after the filing date hereof and prior to the effectiveness of this registration statement, the registrant sells any Unsold Securities under the Prior Registration Statement, the registrant will identify in a pre-effective amendment to this registration statement the updated number of Unsold Securities from the Prior Registration Statement to be included in this registration statement pursuant to Rule 415(a)(6) and the updated amount of new securities to be registered on this registration statement. Pursuant to Rule 415(a)(6), the offering of securities registered under the Prior Registration Statement will be deemed terminated as of the date of effectiveness of this registration statement.

Table 2: Fee Offset Claims and Sources ☑Not Applicable
Registrant or Filer Name Form or Filing Type File Number Initial Filing Date Filing Date Fee Offset Claimed Security Type Associated with Fee Offset Claimed Security Title Associated with Fee Offset Claimed Unsold Securities Associated with Fee Offset Claimed Unsold Aggregate Offering Amount Associated with Fee Offset Claimed Fee Paid with Fee Offset Source
Rules 457(b) and 0-11(a)(2)
Fee Offset Claims N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
Fee Offset Sources N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
Rule 457(p)
Fee Offset Claims N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
Fee Offset Sources N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
Table 3: Combined Prospectuses ☑Not Applicable

Security Type

Security Class Title

Amount of Securities Previously Registered

Maximum Aggregate Offering Price of Securities Previously Registered

Form Type

File Number

Initial Effective Date

N/A N/A N/A N/A N/A N/A N/A N/A