Exhibit 10.1

Execution Version

Settlement Agreement and Mutual Release

This Settlement Agreement and Mutual Release (this “Agreement”) is entered into as of the date of the last signature (the “Effective Date”),

by and between:

Galantos Pharma GmbH i.L., a company in liquidation and incorporated under the laws of the Federal Republic of Germany, with its registered office at Neuweg 16a, 55218 Ingelheim, Germany (“Galantos”),

and

Alpha Cognition Inc., a corporation existing under the laws of Canada, with its principal place of business at 1200 – 750 West Pender Street, Vancouver, BC, V6C 2T8, Canada (“Alpha”),

each a “Party” and together the “Parties.”

RECITALS

Now, therefore, in exchange for and in consideration of the mutual promises and covenants contained herein, along with other good and valuable consideration, the Parties hereby agree as follows:

Capitalized terms used but not otherwise defined herein shall have the meaning as set out in the APA.

Alpha shall pay to Galantos an amount of EUR 51,000 (in words: five million two hundred fourteen thousand two hundred twenty euros) (the “Settlement Payment”).

The Parties acknowledge and agree that approximately EUR 55,000 of the Settlement Payment above economically relates to royalty entitlements accrued during the fiscal year 2025. This attribution is agreed solely for documentation purposes and shall not affect the payment date or payment obligation.

The Settlement Payment shall be sent to Galantos by 15 April 2026 at the latest to the following bank account of Galantos:

[***]

All payments will be made by electronic bank transfer in immediately available funds free of bank charges or other fees and will be deemed validly made when the transfer order is unconditionally and irrevocably made.

The Parties agree that the Settlement Amount payable under this Agreement is not subject to value added tax (“VAT”) pursuant to the provisions of the German Value Added Tax Act; provided that, if any VAT is determined to be due in connection with the Settlement Amount, such VAT shall be borne and paid solely by Galantos, and Alpha shall have no responsibility or liability with respect to such VAT. The Parties further agree that the Settlement Amount represents final payment by Alpha with respect to the Royalty Payments due to Galantos under Clause 3 of the APA, and no further payments shall be due.

3.1 Release of Claims by Galantos.

(a) General Release. Galantos, for itself and its agents, attorneys, successors and assigns, and anyone acting or claiming to act on behalf of Galantos, hereby waives, releases, and forever discharges Alpha and its agents, attorneys, successors and assigns (collectively, the “Released Alpha Parties”) from any and all claims, causes of action or demands (collectively, (“Claims”) for damages, costs, expenses, liabilities, grievances, or other losses, whether known or unknown, that in any way arise from, grow out of, or are related to the APA.

(b) Covenant Not to Sue. Galantos hereby covenants and agrees not to file, commence or initiate any suits, grievances, demands, or causes of action against the Released Alpha Parties based upon or relating to any of the Claims released and forever discharged pursuant to this Agreement. If Galantos breaches this covenant not to sue, Galantos hereby agrees to pay all of the reasonable costs and attorneys’ fees actually incurred by the Released Alpha Parties in defending against such claims, demands, or causes of action, together with such and further damages as may result, directly or indirectly, from that breach. Moreover, Galantos agrees that it will not persuade or instruct any person to file a suit, claim, or complaint with any state or federal court or administrative agency against the Released Alpha Parties. The Parties intend that this paragraph and the release of claims herein be construed as broadly as lawfully possible. Notwithstanding the above, no rights granted to Galantos under this Agreement or the APA shall be released or otherwise waived by the release set forth in this Section 3.1.

3.2 Release of Claims by Alpha.

(a) General Release. Alpha, for itself and its agents, attorneys, successors and assigns, and anyone acting or claiming to act on behalf of Alpha, hereby waives, releases, and forever discharges Galantos and its agents, attorneys, heirs, administrators, executors, successors and assigns (collectively, the “Released Galantos Parties”) from any and all Claims for damages, costs, expenses, liabilities, grievances, or other losses, whether known or unknown, that in any way arise from, grow out of, or are related to the APA.

(b) Covenant Not to Sue. Alpha hereby covenants and agrees not to file, commence or initiate any suits, grievances, demands, or causes of action against the Released Galantos Parties based upon or relating to any of the Claims released and forever discharged pursuant to this Agreement. If Alpha breaches this covenant not to sue, Alpha hereby agrees to pay all of the reasonable costs and attorneys’ fees actually incurred by the Released Galantos Parties in defending against such claims, demands, or causes of action, together with such and further damages as may result, directly or indirectly, from that breach. Moreover, Alpha agrees that Alpha will not persuade or instruct any person to file a suit, claim, or complaint with any state or federal court or administrative agency against the Released Galantos Parties. The Parties intend that this paragraph and the release of claims herein be construed as broadly as lawfully possible. Notwithstanding the above, no rights granted to Alpha under this Agreement or the APA shall be released or otherwise waived by the release set forth in this Section 3.2.

3.3 The Parties agree that the rights and obligations contained in Sections 3.1 and 3.2 shall be subject to payment of the Settlement Amount in full.

Each Party agrees not to make any negative or disparaging statements or remarks concerning the other Party to any third person which might reasonably result in the public disclosure of such negative or disparaging statements or remarks in the form of newspaper or magazine articles, television or radio broadcasts, book publications, speeches, addresses or seminars. The Parties acknowledge and agree that the foregoing provision applies to posting information on the Internet and/or social media outlets. This provision shall be construed as broadly as state and/or federal law permit, but no more broadly than permitted by applicable state and/or federal law. The Parties acknowledge and agree that this Section 4 shall not be interpreted to prevent either Party from providing truthful testimony under oath.

Each Party agrees to maintain absolute confidentiality and secrecy concerning the terms of this Agreement and will not reveal or disseminate by publication in any manner whatsoever this document or any matters pertaining to it to any other person, including but not limited to any past or present employee, officer, manager or director of Company or any media representative, except as required by legal process. This confidentiality provision does not apply to communications necessary between immediate family members, legal and financial planners, or tax preparers who are also bound by this confidentiality provision.

Each Party hereby certifies, represents, and warrants to, and for the benefit of, the other Party, as follows:

Signatures follow on the next page

IN WITNESS WHEREOF, the undersigned have hereunto set their names on the date indicated below.