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Exhibit 23.1

Consent of Independent Registered Public Accounting Firm

 

We consent to the incorporation by reference in the following Registration Statements:

 

(1)
Registration Statement (Form S-8 No. 333-249425) pertaining to the 2016 Equity Incentive Plan, as amended, the 2020 Equity Incentive Plan and the 2020 Employee Share Purchase Plan of Oncorus, Inc.,

 

(2)
Registration Statement (Form S-8 No. 333-263393) pertaining to the 2020 Equity Incentive Plan of Oncorus, Inc.,

 

(3)
Registration Statement (Form S-8 No. 333-254097) pertaining to the 2020 Equity Incentive Plan of Oncorus, Inc., and

 

(4)
Registration Statement (Form S-3 No. 333-260718) of Oncorus, Inc.,

 

of our report dated March 24, 2023, with respect to the consolidated financial statements of Oncorus, Inc. included in this Annual Report (Form 10-K) for the year ended December 31, 2022.

 

 

/s/ Ernst & Young LLP

 

Boston, Massachusetts

March 24, 2023