August 19, 2025 Sean McClain Chief Executive Officer Absci Corporation 18105 SE Mill Plain Blvd Vancouver, WA 98683 Re: Absci Corporation Registration Statement on Form S-3 Filed August 12, 2025 File No. 333-289541 Dear Sean McClain: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Robert Augustin at 202-551-8483 with any questions. Sincerely, Division of Corporation Finance Office of Industrial Applications and Services cc: Maggie Wong