Exhibit 15.1
CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM
We hereby consent to the incorporation by reference in the Registration Statements on Form S-8 (No. 333-223915) and Form F-3 (No. 333-230564) of Sol-Gel Technologies Ltd. of our report dated March 24, 2020 relating to
the financial statements, which appears in this Form 20-F.
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Tel-Aviv, Israel
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/s/Kesselman & Kesselman
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March 24, 2020
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Certified Public Accountants (Isr.)
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A member firm of PricewaterhouseCoopers International Limited
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Kesselman & Kesselman, Trade Tower, 25 Hamered Street, Tel-Aviv 6812508, Israel,
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P.O Box 50005 Tel-Aviv 6150001 Telephone: +972 -3- 7954555, Fax:+972 -3- 7954556, www.pwc.com/il
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