UNITED STATES 

SECURITIES AND EXCHANGE COMMISSION 

Washington, D.C. 20549

FORM 6-K

Report of Foreign Private Issuer   

Pursuant to Rule 13a-16 or 15d-16 

Under the Securities Exchange Act of 1934

For the month of September 2026

Commission File Number 001-38367

SOL-GEL TECHNOLOGIES LTD. 

(Translation of registrant’s name into English)

7 Golda Meir Street 

Ness Ziona 7403650, Israel 

(Address of principal executive offices)

Indicate by check mark whether the registrant files or will file annual reports under cover Form 20-F or Form 40-F.

Form 20-F ☒           Form 40-F ☐

Explanatory Note

On September 17, 2026, Sol-Gel Technologies Ltd. (the “Company”) issued a press release announcing last patient last visit in pivotal Phase 3 clinical trial of SGT-610 in Gorlin Syndrome.

Attached hereto is the following exhibit:

Exhibit 99.1 Press release dated September 17, 2026

Exhibit 99.1 (other than the fourth paragraph thereof) is hereby incorporated by reference into the Company's Registration Statements on Form S-8 (Registration Nos. 333-223915, 333-270477 and 333-286820) and its Registration Statements on Form F-3 (Registrations No. 333-286822 and 333-270478).

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the Registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

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