SCHEDULE 13G

CUSIP No.

282564103

Names of Reporting Persons

Foresite Capital Fund IV, L.P.

Check the appropriate box if a member of a Group (see instructions)

(a)

(b)

Sec Use Only

Citizenship or Place of Organization

DELAWARE

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 1,960,774.00
6	Shared Voting Power 0.00
7	Sole Dispositive Power 1,960,774.00
8	Shared Dispositive Power 0.00

Aggregate Amount Beneficially Owned by Each Reporting Person

1,960,774.00

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

Checkbox not checked

Percent of class represented by amount in row (9)

3.6 %

Type of Reporting Person (See Instructions)

Comment for Type of Reporting Person: Note to Row 5: 1,960,774 shares, except that Foresite Capital Management IV, LLC ("FCM IV"), the general partner of Foresite Capital Fund IV, L.P. ("FCF IV"), may be deemed to have sole power to vote these shares, and James Tananbaum ("Tananbaum"), the managing member of FCM IV, may be deemed to have sole power to vote these shares. Note to Row 6: See response to Row 5. Note to Row 7: 1,960,774 shares, except that FCM IV, the general partner of FCF IV, may be deemed to have sole power to dispose of these shares, and Tananbaum, the managing member of FCM IV, may be deemed to have sole power to dispose of these shares. Note to Row 8: See response to Row 7. Note to Row 11: This percentage is calculated based upon 53,984,337 Common Stock outstanding of Eikon Therapeutics, Inc. (the "Issuer") as of February 4, 2026, as set forth in the Issuer's 424B4 filed with the Securities and Exchange Commission on February 5, 2026.

SCHEDULE 13G

CUSIP No.

282564103

Names of Reporting Persons

Foresite Capital Management IV, LLC

Check the appropriate box if a member of a Group (see instructions)

(a)

(b)

Sec Use Only

Citizenship or Place of Organization

DELAWARE

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 1,960,774.00
6	Shared Voting Power 0.00
7	Sole Dispositive Power 1,960,774.00
8	Shared Dispositive Power 0.00

Aggregate Amount Beneficially Owned by Each Reporting Person

1,960,774.00

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

Checkbox not checked

Percent of class represented by amount in row (9)

3.6 %

Type of Reporting Person (See Instructions)

Comment for Type of Reporting Person: Note to Row 5: 1,960,774 shares, all of which are directly owned by FCF IV. FCM IV, the general partner of FCF IV, may be deemed to have sole power to vote these shares, and Tananbaum, the managing member of FCM IV, may be deemed to have sole power to vote these shares. Note to Row 6: See response to Row 5. Note to Row 7: 1,960,774 shares, all of which are directly owned by FCF IV. FCM IV, the general partner of FCF IV, may be deemed to have sole power to dispose of these shares, and Tananbaum, the managing member of FCM IV, may be deemed to have sole power to dispose of these shares. Note to Row 8: See response to Row 7. Note to Row 11: This percentage is calculated based upon 53,984,337 Common Stock outstanding of the Issuer as of February 4, 2026, as set forth in the Issuer's 424B4 filed with the Securities and Exchange Commission on February 5, 2026.

SCHEDULE 13G

CUSIP No.

282564103

Names of Reporting Persons

Foresite Capital Fund V, L.P.

Check the appropriate box if a member of a Group (see instructions)

(a)

(b)

Sec Use Only

Citizenship or Place of Organization

DELAWARE

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 1,353,168.00
6	Shared Voting Power 0.00
7	Sole Dispositive Power 1,353,168.00
8	Shared Dispositive Power 0.00

Aggregate Amount Beneficially Owned by Each Reporting Person

1,353,168.00

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

Checkbox not checked

Percent of class represented by amount in row (9)

2.5 %

Type of Reporting Person (See Instructions)

Comment for Type of Reporting Person: Note to Row 5: 1,353,168 shares, except that Foresite Capital Management V, LLC ("FCM V"), the general partner of Foresite Capital Fund V, L.P. ("FCF V"), may be deemed to have sole power to vote these shares, and Tananbaum, the managing member of FCM V, may be deemed to have sole power to vote these shares. Note to Row 6: See response to Row 5. Note to Row 7: 1,353,168 shares, except that FCM V, the general partner of FCF V, may be deemed to have sole power to dispose of these shares, and Tananbaum, the managing member of FCM V, may be deemed to have sole power to dispose of these shares. Note to Row 8: See response to Row 7. Note to Row 11: This percentage is calculated based upon 53,984,337 Common Stock outstanding of the Issuer as of February 4, 2026, as set forth in the Issuer's 424B4 filed with the Securities and Exchange Commission on February 5, 2026.

SCHEDULE 13G

CUSIP No.

282564103

Names of Reporting Persons

Foresite Capital Management V, LLC

Check the appropriate box if a member of a Group (see instructions)

(a)

(b)

Sec Use Only

Citizenship or Place of Organization

DELAWARE

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 1,353,168.00
6	Shared Voting Power 0.00
7	Sole Dispositive Power 1,353,168.00
8	Shared Dispositive Power 0.00

Aggregate Amount Beneficially Owned by Each Reporting Person

1,353,168.00

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

Checkbox not checked

Percent of class represented by amount in row (9)

2.5 %

Type of Reporting Person (See Instructions)

Comment for Type of Reporting Person: Note to Row 5: 1,353,168 shares, all of which are directly owned by FCF V. FCM V, the general partner of FCF V, may be deemed to have sole power to vote these shares, and Tananbaum, the managing member of FCM V, may be deemed to have sole power to vote these shares. Note to Row 6: See response to Row 5. Note to Row 7: 1,353,168 shares, all of which are directly owned by FCF V. FCM V, the general partner of FCF V, may be deemed to have sole power to dispose of these shares, and Tananbaum, the managing member of FCM V, may be deemed to have sole power to dispose of these shares. Note to Row 8: See response to Row 7. Note to Row 11: This percentage is calculated based upon 53,984,337 Common Stock outstanding of the Issuer as of February 4, 2026, as set forth in the Issuer's 424B4 filed with the Securities and Exchange Commission on February 5, 2026.

SCHEDULE 13G

CUSIP No.

282564103

Names of Reporting Persons

Foresite Capital Opportunity Fund V, L.P.

Check the appropriate box if a member of a Group (see instructions)

(a)

(b)

Sec Use Only

Citizenship or Place of Organization

DELAWARE

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 425,852.00
6	Shared Voting Power 0.00
7	Sole Dispositive Power 425,852.00
8	Shared Dispositive Power 0.00

Aggregate Amount Beneficially Owned by Each Reporting Person

425,852.00

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

Checkbox not checked

Percent of class represented by amount in row (9)

0.8 %

Type of Reporting Person (See Instructions)

Comment for Type of Reporting Person: Note to Row 5: 425,852 shares, except that Foresite Capital Opportunity Management V, LLC ("FCM Opp V"), the general partner of Foresite Capital Opportunity Fund V, L.P. ("FCF Opp V"), may be deemed to have sole power to vote these shares, and Tananbaum, the managing member of FCM Opp V, may be deemed to have sole power to vote these shares. Note to Row 6: See response to Row 5. Note to Row 7: 425,852 shares, except that FCM Opp V, the general partner of FCF Opp V, may be deemed to have sole power to dispose of these shares, and Tananbaum, the managing member of FCM Opp V, may be deemed to have sole power to dispose of these shares. Note to Row 8: See response to Row 7. Note to Row 11: This percentage is calculated based upon 53,984,337 Common Stock outstanding of the Issuer as of February 4, 2026, as set forth in the Issuer's 424B4 filed with the Securities and Exchange Commission on February 5, 2026.

SCHEDULE 13G

CUSIP No.

282564103

Names of Reporting Persons

Foresite Capital Opportunity Management V, LLC

Check the appropriate box if a member of a Group (see instructions)

(a)

(b)

Sec Use Only

Citizenship or Place of Organization

DELAWARE

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 425,852.00
6	Shared Voting Power 0.00
7	Sole Dispositive Power 425,852.00
8	Shared Dispositive Power 0.00

Aggregate Amount Beneficially Owned by Each Reporting Person

425,852.00

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

Checkbox not checked

Percent of class represented by amount in row (9)

0.8 %

Type of Reporting Person (See Instructions)

Comment for Type of Reporting Person: Note to Row 5: 425,852 shares, all of which are directly owned by FCF Opp V. FCM Opp V, the general partner of FCF Opp V, may be deemed to have sole power to vote these shares, and Tananbaum, the managing member of FCM Opp V, may be deemed to have sole power to vote these shares. Note to Row 6: See response to Row 5. Note to Row 7: 425,852 shares, all of which are directly owned by FCF Opp V. FCM Opp V, the general partner of FCF Opp V, may be deemed to have sole power to dispose of these shares, and Tananbaum, the managing member of FCM Opp V, may be deemed to have sole power to dispose of these shares. Note to Row 8: See response to Row 7. Note to Row 11: This percentage is calculated based upon 53,984,337 Common Stock outstanding of the Issuer as of February 4, 2026, as set forth in the Issuer's 424B4 filed with the Securities and Exchange Commission on February 5, 2026.

SCHEDULE 13G

CUSIP No.

282564103

Names of Reporting Persons

Foresite Capital VI-A, LLC

Check the appropriate box if a member of a Group (see instructions)

(a)

(b)

Sec Use Only

Citizenship or Place of Organization

DELAWARE

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 408,725.00
6	Shared Voting Power 0.00
7	Sole Dispositive Power 408,725.00
8	Shared Dispositive Power 0.00

Aggregate Amount Beneficially Owned by Each Reporting Person

408,725.00

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

Checkbox not checked

Percent of class represented by amount in row (9)

0.8 %

Type of Reporting Person (See Instructions)

Comment for Type of Reporting Person: Note to Row 5: 408,725 shares, except that Foresite Capital VI-A Management, LLC ("FCM VI-A"), the managing member of Foresite Capital VI-A, LLC ("FC VI-A"), may be deemed to have sole power to vote these shares, and Tananbaum, the managing member of FC VI-A, may be deemed to have sole power to vote these shares. Note to Row 6: See response to Row 5. Note to Row 7: 408,725 shares, except that FCM VI-A, the managing member of FC VI-A, may be deemed to have sole power to dispose of these shares, and Tananbaum, the managing member of FCM VI-A, may be deemed to have sole power to dispose of these shares. Note to Row 8: See response to Row 7. Note to Row 11: This percentage is calculated based upon 53,984,337 Common Stock outstanding of the Issuer as of February 4, 2026, as set forth in the Issuer's 424B4 filed with the Securities and Exchange Commission on February 5, 2026.

SCHEDULE 13G

CUSIP No.

282564103

Names of Reporting Persons

Foresite Capital VI-A Management, LLC

Check the appropriate box if a member of a Group (see instructions)

(a)

(b)

Sec Use Only

Citizenship or Place of Organization

DELAWARE

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 408,725.00
6	Shared Voting Power 0.00
7	Sole Dispositive Power 408,725.00
8	Shared Dispositive Power 0.00

Aggregate Amount Beneficially Owned by Each Reporting Person

408,725.00

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

Checkbox not checked

Percent of class represented by amount in row (9)

0.8 %

Type of Reporting Person (See Instructions)

Comment for Type of Reporting Person: Note to Row 5: 408,725 shares, all of which are directly owned by FC VI-A. FCM VI-A, the managing member of FC VI-A, may be deemed to have sole power to vote these shares, and Tananbaum, the managing member of FCM VI-A, may be deemed to have sole power to vote these shares. Note to Row 6: See response to Row 5. Note to Row 7: 408,725 shares, all of which are directly owned by FC VI-A. FCM VI-A, the managing member of FC VI-A, may be deemed to have sole power to dispose of these shares, and Tananbaum, the managing member of FCM VI-A, may be deemed to have sole power to dispose of these shares. Note to Row 8: See response to Row 7. Note to Row 11: This percentage is calculated based upon 53,984,337 Common Stock outstanding of the Issuer as of February 4, 2026, as set forth in the Issuer's 424B4 filed with the Securities and Exchange Commission on February 5, 2026.

SCHEDULE 13G

CUSIP No.

282564103

Names of Reporting Persons

James B. Tananbaum

Check the appropriate box if a member of a Group (see instructions)

(a)

(b)

Sec Use Only

Citizenship or Place of Organization

UNITED STATES

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 4,148,519.00
6	Shared Voting Power 0.00
7	Sole Dispositive Power 4,148,519.00
8	Shared Dispositive Power 0.00

Aggregate Amount Beneficially Owned by Each Reporting Person

4,148,519.00

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

Checkbox not checked

Percent of class represented by amount in row (9)

7.7 %

Type of Reporting Person (See Instructions)

Comment for Type of Reporting Person: Note to Row 5: 4,148,519 shares, of which 1,960,774 shares are directly owned by FCF IV, 1,353,168 shares are directly owned by FCF V, 425,852 shares are directly owned by FCF Opp V and 408,725 shares are directly owned by FC VI-A. Tananbaum is the managing member of each of FCM IV, which is the general partner of FCF IV, FCM V, which is the general partner of FCF V, FCM Opp V, which is the general partner of FCF Opp V and FCM VI-A, which is the managing member of FC VI-A. Tananbaum may be deemed to have sole power to vote these shares. Note to Row 6: See response to Row 5. Note to Row 7: 4,148,519 shares, of which 1,960,774 shares are directly owned by FCF IV, 1,353,168 shares are directly owned by FCF V, 425,852 shares are directly owned by FCF Opp V and 408,725 shares are directly owned by FC VI-A. Tananbaum is the managing member of each of FCM IV, which is the general partner of FCF IV, FCM V, which is the general partner of FCF V, FCM Opp V, which is the general partner of FCF Opp V and FCM VI-A, which is the managing member of FC VI-A. Tananbaum may be deemed to have sole power to dispose of these shares. Note to Row 8: See response to Row 7. Note to Row 11: This percentage is calculated based upon 53,984,337 Common Stock outstanding of the Issuer as of February 4, 2026, as set forth in the Issuer's 424B4 filed with the Securities and Exchange Commission on February 5, 2026.

SCHEDULE 13G

Item 1.

(a)

Name of issuer:

Eikon Therapeutics, Inc.

(b)

Address of issuer's principal executive offices:

230 Harriet Tubman Way, Millbrae, CA 94030

Item 2.

(a)

Name of person filing:

This Schedule is filed by Foresite Capital Fund IV, L.P., a Delaware limited partnership, Foresite Capital Management IV, LLC, a Delaware limited liability company, Foresite Capital Fund V, L.P., a Delaware limited partnership, Foresite Capital Management V, LLC, a Delaware limited liability company, Foresite Capital Opportunity Fund V, L.P., a Delaware limited partnership, Foresite Capital Opportunity Management V, LLC, a Delaware limited liability company, Foresite Capital VI-A, LLC, a Delaware limited liability company, Foresite Capital VI-A Management, LLC, a Delaware limited liability company and James Tananbaum. The foregoing entities and individuals are collectively referred to as the "Reporting Persons."

(b)

Address or principal business office or, if none, residence:

c/o Foresite Capital Management 9200 W. Sunset Boulevard, Suite 515 West Hollywood, CA 90069

(c)

Citizenship:

See Row 4 of cover page for each Reporting Person.

(d)

Title of class of securities:

Common Stock, par value $0.0001

(e)

CUSIP No.:

282564103

Item 3.

If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:

(a)

Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);

(b)

Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);

(c)

Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);

(d)

Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);

(e)

An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);

(f)

An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);

(g)

A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);

(h)

A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);

(i)

A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);

(j)

A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J). If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J),
please specify the type of institution:

(k)

Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).

Item 4.

Ownership

(a)

Amount beneficially owned:

See Row 9 of cover page for each Reporting Person.

(b)

Percent of class:

See Row 11 of cover page for each Reporting Person.

(c)

Number of shares as to which the person has:

(i) Sole power to vote or to direct the vote:

See Row 5 of cover page for each Reporting Person.

(ii) Shared power to vote or to direct the vote:

See Row 6 of cover page for each Reporting Person.

(iii) Sole power to dispose or to direct the disposition of:

See Row 7 of cover page for each Reporting Person.

(iv) Shared power to dispose or to direct the disposition of:

See Row 8 of cover page for each Reporting Person.

Item 5.

Ownership of 5 Percent or Less of a Class.

Not Applicable

Item 6.

Ownership of more than 5 Percent on Behalf of Another Person.

If any other person is known to have the right to receive or the power to direct the receipt of dividends from, or the proceeds from the sale of, such securities, a statement to that effect should be included in response to this item and, if such interest relates to more than 5 percent of the class, such person should be identified. A listing of the shareholders of an investment company registered under the Investment Company Act of 1940 or the beneficiaries of employee benefit plan, pension fund or endowment fund is not required.

Under certain circumstances set forth in the limited partnership agreements of FCF IV, FCF V and FCF Opp V and the limited liability company agreements of FC VI-A, FCM VI-A, FCM IV, FCM V and FCM Opp V, the partners or members, as the case may be, of each of such entities may be deemed to have the right to receive dividends from, or the proceeds from the sale of, shares of the Issuer directly or indirectly owned by each such entity of which they are a partner or member.

Item 7.

Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.

Not Applicable

Item 8.

Identification and Classification of Members of the Group.

Not Applicable

Item 9.

Notice of Dissolution of Group.

Not Applicable

Item 10.

Certifications:

By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11.

SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

Foresite Capital Fund IV, L.P.

Signature:	/s/ James Tananbaum
Name/Title:	James Tananbaum, Managing Member of the General Partner
Date:	02/11/2026

Foresite Capital Management IV, LLC

Signature:	/s/ James Tananbaum
Name/Title:	James Tananbaum, Managing Member
Date:	02/11/2026

Foresite Capital Fund V, L.P.

Signature:	/s/ James Tananbaum
Name/Title:	James Tananbaum, Managing Member of the General Partner
Date:	02/11/2026

Foresite Capital Management V, LLC

Signature:	/s/ James Tananbaum
Name/Title:	James Tananbaum, Managing Member
Date:	02/11/2026

Foresite Capital Opportunity Fund V, L.P.

Signature:	/s/ James Tananbaum
Name/Title:	James Tananbaum, Managing Member of the General Partner
Date:	02/11/2026

Foresite Capital Opportunity Management V, LLC

Signature:	/s/ James Tananbaum
Name/Title:	James Tananbaum, Managing Member
Date:	02/11/2026

Foresite Capital VI-A, LLC

Signature:	/s/ James Tananbaum
Name/Title:	James Tananbaum, Managing Member of the Managing Member
Date:	02/11/2026

Foresite Capital VI-A Management, LLC

Signature:	/s/ James Tananbaum
Name/Title:	James Tananbaum, Managing Member
Date:	02/11/2026

James B. Tananbaum

Signature:	/s/ James Tananbaum
Name/Title:	James Tananbaum
Date:	02/11/2026

Exhibit Information

Exhibit A Agreement of Joint Filing The undersigned hereby agree that a single Schedule 13G (or any amendment thereto) relating to the Common Stock of the Issuer shall be filed on behalf of each of the undersigned and that this Agreement shall be filed as an exhibit to such Schedule 13G. Date: February 11, 2026 FORESITE CAPITAL FUND IV, L.P. By: FORESITE CAPITAL MANAGEMENT IV, LLC Its: General Partner By: /s/ James Tananbaum Name: James Tananbaum Title: Managing Member FORESITE CAPITAL MANAGEMENT IV, LLC By: /s/ James Tananbaum Name: James Tananbaum Title: Managing Member FORESITE CAPITAL FUND V, L.P. By: FORESITE CAPITAL MANAGEMENT V, LLC Its: General Partner By: /s/ James Tananbaum Name: James Tananbaum Title: Managing Member FORESITE CAPITAL MANAGEMENT V, LLC By: /s/ James Tananbaum Name: James Tananbaum Title: Managing Member FORESITE CAPITAL OPPORTUNITY FUND V, L.P. By: FORESITE CAPITAL OPPORTUNITY MANAGEMENT V, LLC Its: Managing Member By: /s/ James Tananbaum Name: James Tananbaum Title: Managing Member FORESITE CAPITAL OPPORTUNITY MANAGEMENT V, LLC By: /s/ James Tananbaum Name: James Tananbaum Title: Managing Member FORESITE CAPITAL VI-A, LLC By: FORESITE CAPITAL VI-A MANAGEMENT, LLC Its: Managing Member By: /s/ James Tananbaum Name: James Tananbaum Title: Managing Member FORESITE CAPITAL VI-A MANAGEMENT, LLC By: /s/ James Tananbaum Name: James Tananbaum Title: Managing Member JAMES TANANBAUM By: /s/ James Tananbaum Name: James Tananbaum