United States securities and exchange commission logo January 14, 2021 Michael D. West President and Chief Executive Officer AgeX Therapeutics, Inc. 101 Marina Village Parkway, Suite 201 Alameda, CA 94501 Re: AgeX Therapeutics, Inc. Registration Statement on Form S-3 Filed January 8, 2021 File No. 333-251988 Dear Mr. West: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Deanna Virginio at 202-551-4530 with any questions. Sincerely, Division of Corporation Finance Office of Life Sciences cc: Richard S. Soroko, Esq.