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Exhibit 5.1 |
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P.O. Box 7113
1007 JC Amsterdam
Beethovenstraat 400
1082 PR Amsterdam
T +31 20 71 71 000
F +31 20 71 71 111
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Amsterdam, 7 May 2026.
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| a. |
drafts of documents reviewed by us will be signed in the form of those drafts, each copy of a document conforms to the original, each original is authentic, and each signature is the genuine signature of the
individual purported to have placed that signature;
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| b. |
if any signature under any document is an electronic signature (as opposed to a handwritten (“wet ink”) signature) only, it is either a qualified electronic signature within the meaning of the eIDAS Regulation, or
the method used for signing is otherwise sufficiently reliable;
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| c. |
the Registration Statement has been declared effective by the SEC in the form reviewed by us;
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| e. |
(i) no internal regulations (reglementen) have been adopted by any corporate body of the Company which would affect the validity of the resolutions recorded in the
Resolutions and (ii) the Current Articles are the Articles of Association currently in force and as they will be in force at each Relevant Moment;
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| f. |
(i) at each Relevant Moment, the resolutions recorded in the Resolutions shall be in full force and effect and (ii) at each Relevant Moment, the factual statements made and the confirmations given in the Resolutions
and in each Deed of Issue shall be complete and correct;
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| g. |
at each Relevant Moment, the authorised share capital (maatschappelijk kapitaal) of the Company shall allow for the
issuance of the Offer Shares;
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| h. |
at a Relevant Moment, the relevant Deed of Issue shall have been validly signed and executed on behalf of the Company; and
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| i. |
the Offering, to the extent made in the Netherlands, has been, is and will be made in conformity with the Prospectus Regulation and the rules promulgated thereunder.
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| 1. |
The Company has been duly incorporated as a besloten vennootschap met beperkte aansprakelijkheid and is validly existing as a naamloze
vennootschap.
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| A. |
Opinion 1 must not be read to imply that the Company cannot be dissolved (ontbonden). A company such as the Company may be dissolved, inter alia by the competent court at the
request of the company’s board of directors, any interested party (belanghebbende) or the public prosecution office in certain circumstances, such as when there are certain defects in the incorporation
of the company. Any such dissolution will not have retro-active effect.
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| B. |
Pursuant to Section 2:7 DCC, any transaction entered into by a legal entity may be nullified by the legal entity itself or its liquidator in bankruptcy proceedings (curator)
if the objects of that entity were transgressed by the transaction and the other party to the transaction knew or should have known this without independent investigation (wist of zonder eigen onderzoek moest
weten). The Dutch Supreme Court (Hoge Raad der Nederlanden) has ruled that in determining whether the objects of a legal entity are transgressed, not only the description of the objects in
that legal entity’s articles of association (statuten) is decisive, but all (relevant) circumstances must be taken into account, in particular whether the interests of the legal entity were served by
the transaction. Based on the objects clause contained in the Current Articles, we have no reason to believe that, by entering into the Reviewed Documents, the Company would transgress the description of the objects contained in its Articles
of Association. However, we cannot assess whether there are other relevant circumstances that must be taken into account, in particular whether the interests of the Company are served by entering into the Reviewed Documents since this is a
matter of fact.
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| C. |
Pursuant to Section 2:98c DCC, a company such as the Company may grant loans (leningen verstrekken) only in
accordance with the restrictions set out in Section 2:98c DCC, and may not provide security (zekerheid stellen), give a price guarantee (koersgarantie geven) or otherwise bind itself, whether jointly and severally or otherwise with or for third parties (zich op andere wijze sterk maken of zich hoofdelijk of anderszins naast of voor anderen verbinden) with a view to (met het oog op) the subscription or acquisition by third parties of shares in its share capital or depository receipts. This prohibition also applies to its subsidiaries (dochtervennootschappen). It is generally assumed that a transaction entered into in violation of Section 2:98c DCC is null and void (nietig). Based
on the content of the Reviewed Documents, we have no reason to believe that the Company or its subsidiaries will violate Section 2:98c DCC in connection with the issue of the Offer Shares. However, we
cannot confirm this definitively, since the determination of whether a company (or a subsidiary) has provided security, has given a price guarantee or has otherwise bound itself, with a view to the subscription or acquisition by third parties
of shares in its share capital or depository receipts, as described above, is a matter of fact.
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| D. |
The opinions expressed in this opinion letter may be limited or affected by:
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| a. |
rules relating to Insolvency Proceedings or similar proceedings under a foreign law and other rules affecting creditors’ rights generally;
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| b. |
the provisions of fraudulent preference and fraudulent conveyance (Actio Pauliana) and similar rights available in other jurisdictions to insolvency practitioners and insolvency office holders in
bankruptcy proceedings or creditors;
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| c. |
claims based on tort (onrechtmatige daad);
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| d. |
sanctions and measures, including but not limited to those concerning export control, pursuant to European Union regulations, under the Dutch Sanctions Act 1977 (Sanctiewet 1977) or other
legislation;
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| e. |
the Anti-Boycott Regulation, Anti Money Laundering Laws and related legislation;
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| f. |
any intervention, recovery or resolution measure by any regulatory or other authority or governmental body in relation to financial enterprises or their affiliated entities; and
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| g. |
the rules of force majeure (niet toerekenbare tekortkoming), reasonableness and fairness (redelijkheid en billijkheid), suspension (opschorting), dissolution (ontbinding), unforeseen circumstances (onvoorziene omstandigheden) and vitiated consent (i.e.,
duress (bedreiging), fraud (bedrog), abuse of circumstances (misbruik van omstandigheden) and error (dwaling)) or a difference of intention (wil) and declaration (verklaring).
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| F. |
This opinion letter does not purport to express any opinion or view on the operational rules and procedures of any clearing or settlement system or agency.
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“Anti Money Laundering Laws”
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The European Anti-Money Laundering Directives, as implemented in the Netherlands in the Money Laundering and Terrorist Financing Prevention Act (Wet ter voorkoming van witwassen en financieren van terrorisme) and the Dutch Criminal Code (Wetboek van Strafrecht).
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“Anti-Boycott Regulation”
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The Council Regulation (EC) No 2271/96 of 22 November 1996 on protecting against the effects of the extra-territorial application of legislation adopted by a third country, and actions based
thereon or resulting therefrom.
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“Articles of Association”
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The Company’s articles of association (statuten) as they read from time to time.
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“Bankruptcy Code”
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The Dutch Bankruptcy Code (Faillissementswet).
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“Board”
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The Company’s board of directors (bestuur).
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“Commercial Register”
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The Dutch Commercial Register (handelsregister).
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“Company”
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InflaRx N.V., a public company with limited liability (naamloze vennootschap),
registered with the Commercial Register under number 68904312.
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“Corporate Documents”
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The Deed of Incorporation, the Deed of Conversion, the Current Articles, the Resolutions, the Registration Statement and the Prospectus Supplement.
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“Current Articles”
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The Articles of Association as they read immediately after the execution of a deed of amendment dated April 23, 2026.
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“DCC”
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The Dutch Civil Code (Burgerlijk Wetboek).
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“Deed of Conversion”
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The deed of conversion and amendment to the Articles of Association dated November 8, 2017.
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“Deed of Incorporation”
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The Company’s deed of incorporation (akte van oprichting) dated June 6, 2017.
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“Deed of Issue”
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The draft deed of issue of the Offer Shares, prepared by us with reference 59.624.818.
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“eIDAS Regulation”
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Regulation (EU) No 910/2014 of the European Parliament and of the Council of 23 July 2014 on electronic identification and trust services for electronic transactions in the internal market and
repealing Directive 1999/93/EC.
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“General Meeting”
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The Company’s general meeting (algemene vergadering).
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“Insolvency Proceedings”
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Any insolvency proceedings within the meaning of Regulation (EU) 2015/848 of the European Parliament and of the Council of 20 May 2015 on insolvency proceedings (recast), as amended by
Regulation (EU) 2021/2260 of the European Parliament and of the Counsel of 15 December 2021, listed in Annex A thereto and any statutory proceedings for the restructuring of debts (akkoordprocedure)
pursuant to the Bankruptcy Code.
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“NautaDutilh”
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NautaDutilh N.V.
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“the Netherlands”
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The European territory of the Kingdom of the Netherlands and “Dutch” is in or from the Netherlands.
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“Offer Shares”
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75,000,000 Ordinary Shares.
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“Offering”
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The offering of Ordinary Shares as contemplated by the Prospectus Supplement.
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“Ordinary Shares”
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Ordinary shares in the Company’s capital, with a nominal value of EUR 0.12 each.
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“Prospectus Regulation”
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Regulation (EU) 2017/1129 of the European Parliament and of the Council of 14 June 2017 on the prospectus to be published when securities are offered to the public or admitted to trading on a
regulated market, and repealing Directive 2003/71/EC.
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“Prospectus Supplement”
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The prospectus supplement to the Registration Statement filed with the SEC, in connection with the Offering in the form reviewed by us.
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“Registration Statement”
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The Company’s registration statement on Form F-3 (No. 333-273058) filed with the SEC.
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“Relevant Moment”
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The moment when Offer Shares are issued pursuant to the execution of a Deed of Issue.
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“Resolutions”
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Each of the following:
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a. The written resolutions of the Board, dated May 6, 2026; and
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b. the resolutions of the General Meeting adopted in the meeting held on April 23, 2026, as reflected in the convening
notice and explanatory notes for that General Meeting that are published on the Company’s website on the date of this opinion letter; and
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c. the written resolutions of the pricing committee dated May 6, 2026.
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“Reviewed Documents”
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Each Deed of Issue and the Underwriting Agreement.
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“SEC”
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The United States Securities and Exchange Commission.
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“Underwriters”
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The Underwriters, as defined in the Underwriting Agreement.
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“Underwriting Agreement”
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The underwriting agreement entered into between the Company and Guggenheim Securities, LLC, as representative of the Underwriters in connection with the Offering, dated May 6, 2026.
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