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The Board of Directors

Personalis, Inc.

6600 Dumbarton Circle

Fremont, CA 94555

The Board of Directors:

We hereby consent to the inclusion of our opinion letter, dated July 19, 2026, to the Board of Directors of Personalis, Inc. as Annex B to, and reference to such opinion letter under the headings “Summary Term Sheet,” “Questions and Answers,” “Special Factors—Background of the Mergers,” “Special Factors—Background of the Mergers,” “Special Factors—Reasons for the Mergers; Recommendation of the Personalis Board of Directors; Fairness,” “Special Factors—Unaudited Prospective Financial Information—Personalis” and “Special Factors—Opinions of Personalis’ Financial Advisors” in, the proxy statement/prospectus of Tempus AI, Inc. (“Tempus”), which proxy statement/prospectus forms a part of the registration statement on Form S-4 of Tempus (the “Registration Statement”).

In giving such consent, we do not admit that we come within the category of persons whose consent is required under Section 7 of the Securities Act of 1933, as amended (the “Act”), or the rules and regulations of the Securities and Exchange Commission (the “SEC”) promulgated thereunder nor do we hereby admit that we are experts with respect to any part of the Registration Statement within the meaning of the term “experts” as used in the Act or the rules and regulations of the SEC promulgated thereunder.

 

August 31, 2026