Please wait

Exhibit 21.1

The Company’s principal subsidiaries as of December 31, 2025 are listed below. All other subsidiaries of the Company, if considered in the aggregate as a single affiliate, would not constitute a significant subsidiary of the Company.

Subsidiaries (Alphabetically)State of Inc.
ABC Medical, LLCSOUTH CAROLINA
Absolute Respiratory Care, LLCRHODE ISLAND
Access Medical, LLCMICHIGAN
Accucare Medical Equipment, LLCOKLAHOMA
ActivStyle Holding CompanyDELAWARE
AdaptHealth - Missouri LLCMISSOURI
AdaptHealth Holdings LLCDELAWARE
AdaptHealth Intermediate HoldCo LLCDELAWARE
AdaptHealth LLCDELAWARE
AdaptHealth Minnesota LLCMINNESOTA
AdaptHealth New England LLCDELAWARE
AdaptHealth Patient Care Solutions LLCPENNSYLVANIA
AdaptHealth West LLCDELAWARE
Aerocare Home Medical Equipment, Inc.TEXAS
Aerocare Home Medical Equipment, Inc. (MO)MISSOURI
Aerocare Home Medical, Inc.TEXAS
Aerocare, Inc.NEVADA
Agile Medical LLCPENNSYLVANIA
Agilis Med Holdings LLCDELAWARE
AirCare Home Respiratory, LLCCALIFORNIA
Airway Oxygen, Inc.MICHIGAN
All American Oxygen, Inc.KENTUCKY
American Ancillaries, Inc.NEVADA
American Home Medical, Inc.FLORIDA
America's Health Care at Home, LLCDELAWARE
Americoast Maryland LLCDELAWARE
Ameri-Quipt of North Carolina, Inc.NORTH CAROLINA
Atlantic Medical Supply, Inc.FLORIDA
Atlantic Medical, Inc.VIRGINIA
Austin Respiratory Equipment, Inc.FLORIDA
Beacon Respiratory Services of Georgia, Inc.DELAWARE
Beacon Respiratory Services, Inc.DELAWARE
Bennett Medical Services LLCNEVADA
BestMED Respiratory, Inc.IOWA
BHS, Inc.KENTUCKY


Subsidiaries (Alphabetically)State of Inc.
Bird & Bear Medical, Inc.ARKANSAS
Blue Dot Medical, LLCMISSISSIPPI
Bluegrass Oxygen, Inc.KENTUCKY
B-Pharm, Inc.MISSOURI
Braden Partners, L.P.CALIFORNIA
Brannons Rentals and Sales, Inc.CALIFORNIA
Bradley DME LLCTENNESSEE
Breathe Grace Medical Supply, LLCMARYLAND
Buffalo Wheelchair, Inc.NEW YORK
BuypapUSA.com, Inc.OREGON
Cair Respiratory Services LLCMARYLAND
Cape Medical Supply, LLCMASSACHUSETTS
Care Plus Oxygen, LLCPENNSYLVANIA
Carmichaels Home Medical Equipment, Inc.GEORGIA
Choice Medical Health Care, LLCILLINOIS
Choice Respiratory & Medical Equipment, Inc.VIRGINIA
Clay Home Medical, Inc.VIRGINIA
Clearview Medical IncorporatedTEXAS
Community Medical Supply, Inc.IOWA
Community Surgical Supply of Toms River LLCDELAWARE
Cornerstone Medical Services -- Midwest, LLCOHIO
Cornerstone Medical Services of Columbus, LLCOHIO
CressCare Medical, Inc.PENNSYLVANIA
Desloge Home Oxygen and Medical Equipment, Inc.FLORIDA
Diabetes Management & Supplies LLCLOUISIANA
Diabetes Supply Center of the Midlands LLCNEBRASKA
DSCM Holdco IncNEBRASKA
Edge Medical Supply, LLCTEXAS
Express Medical Supply, LLCTEXAS
Family Home Medical Supply LLCPENNSYLVANIA
Family Medical Supply LLCNORTH CAROLINA
First Choice In-HomeCare, Inc.VIRGINIA
First Choice Home Medical Equipment, LLCDELAWARE
First Choice Medical Equipment, Inc.ILLINOIS
Fletchers Medical Supplies IncFLORIDA
Florida Home Cair, Inc.FLORIDA
Florida Home Medical Supply, LLCFLORIDA
Freedom Respiratory, Inc.VIRGINIA
Gammie Homecare Inc.HAWAII
Georgia Home Medical - Columbus, Inc.GEORGIA


Subsidiaries (Alphabetically)State of Inc.
Georgia Home Medical, Inc.GEORGIA
GME Medical Supply, Inc.VIRGINIA
Gould’s Discount Medical, LLCKENTUCKY
Grace Healthcare IncorporatedLOUISIANA
Grace Healthcare Medical, Inc.MISSISSIPPI
Grace Healthcare, Inc.MISSISSIPPI
Grace Medical Equipment, Inc.ALABAMA
Grace Medical, Inc.FLORIDA
Halprin, IncorporatedNEW YORK
Health Complex Medical, LLCCONNECTICUT
Health Products Plus, Inc.GEORGIA
Healthline Medical Equipment, LLCTEXAS
Healthy Living Medical Supply, LLCMICHIGAN
Heartland Medical Equipment, Inc.MISSOURI
Home Care Medical, Inc.WISCONSIN
Home Medical Express, Inc.ILLINOIS
Home Medical Products and Services LLCWISCONSIN
Home Mediservice, LLCMARYLAND
Home Nursing Care, Inc.VIRGINIA
Home Respiratory Solution's, Inc.FLORIDA
Hometown Respiratory Consultants, LLCTENNESSEE
Hub's Home Oxygen & Medical Supplies, LLCPENNSYLVANIA
Huey’s Home Medical, LLCDELAWARE
Hurst Medical Equipment, Inc.WEST VIRGINIA
J.M.R. Medical, LLCDELAWARE
Keene Medical Products LLCNEW HAMPSHIRE
Lamar, LLCFLORIDA
LCP Solara Blocker CorpDELAWARE
Legacy Medical, LLCOHIO
Lehigh Valley Respiratory Care - Lancaster, LLCPENNSYLVANIA
LifeHME, Inc.SOUTH CAROLINA
Loftis Home Medical, LLCNORTH CAROLINA
Lookout Medical Services, Inc.TENNESSEE
Louisville O2, Inc.KENTUCKY
Lovell Medical Supply, Inc.NORTH CAROLINA
Madison County Medical Equipment, Inc.IOWA
Major Medical Supply of Brighton, LLCCOLORADO
Major Medical Supply of Colorado Springs, LLCCOLORADO
Major Medical Supply of Denver, LLCCOLORADO
Major Medical Supply of Fort Collins, LLCCOLORADO


Subsidiaries (Alphabetically)State of Inc.
Major Medical Supply of Greeley, LLCCOLORADO
Major Medical Supply, LLCCOLORADO
Manor Respiratory Care, Inc.TENNESSEE
Matrix Medical, LLCFLORIDA
McFarland Group, LLCTENNESSEE
Med Star Surgical & Breathing Equipment Inc.NEW YORK
Med Way Medical, Inc.UTAH
MedBridge Home Medical LLCDELAWARE
Med-Equip, Inc.PENNSYLVANIA
Medical Logic Ft. Walton, Inc.ALABAMA
Medical Logic, Inc.ALABAMA
Medical Necessities and Services, LLCTENNESSEE
Medidex, LLCMISSOURI
Medlogic Anniston, Inc.ALABAMA
Medlogic Birmingham, Inc.ALABAMA
Medstar Holdings LLCDELAWARE
Medway Medical Equipment, LLCTEXAS
Mississippi HMA DME, LLCMISSISSIPPI
MME II, LLCTEXAS
Montgomery Medical Supply, Inc.ALABAMA
New England Home Medical Equipment LLCMASSACHUSETTS
Northshore Respiratory and Rehab Specialties, Inc.LOUISIANA
NRE Holding LLCDELAWARE
Ocean Breeze Infusion Care LLCNEW YORK
Ocean Home Health of PA LLCPENNSYLVANIA
Ocean Home Health Supply LLCNEW JERSEY
Ogles Oxygen, LLCSOUTH CAROLINA
Olympia Respiratory Services LLCWASHINGTON
Ours CorporationILLINOIS
Oxygen & Sleep Associates, Inc.TENNESSEE
Oxygen One, Inc.WISCONSIN
Oxygen Supply Shop, LLCNEW JERSEY
Pal-Med, LLCSOUTH CAROLINA
Palmetto Oxygen, LLCSOUTH CAROLINA
Parrish Home Medical, Inc.SOUTH CAROLINA
Peach Home Health Care, Inc.GEORGIA
Pharmacy, Inc.DELAWARE
Pinnacle Medical Solutions LLCMISSISSIPPI
Pinnacle Medical Solutions, Inc.DELAWARE
PPS HME Holdings LLCDELAWARE


Subsidiaries (Alphabetically)State of Inc.
PPS HME LLCDELAWARE
Prattville Medical Equipment, Inc.ALABAMA
Premier Home Care, Inc.KENTUCKY
Premier Home Medical Equipment Services, LLCPENNSYLVANIA
Promise Medical, Inc.TEXAS
Provider Plus, LLCMISSOURI
Pumps It IncTEXAS
PVHS Home Medical Supply, LLCCOLORADO
Quality Home Medical, Inc.SOUTH CAROLINA
Quality Medical Services, Inc.IOWA
Quality Respi-Care, Inc.GEORGIA
Reliable Medical Equipment, LLCSOUTH CAROLINA
Reliable Medical of Conway, LLCSOUTH CAROLINA
Resp-I-Care, LLCTENNESSEE
Respiratory Home Care of Bristol, LLCTENNESSEE
Respiratory Services of Western New York IncNEW YORK
Respracare, Inc.NORTH CAROLINA
Roberts Home Medical, LLCMARYLAND
Rocky Mountain Medical Equipment, Inc.COLORADO
Rocky Mountain Medical Equipment, LLCCOLORADO
Royal Homestar LLCDELAWARE
Royal Medical Supply LLCNEW JERSEY
Skinny, LLCFLORIDA
Skoro Enterprises LLCTEXAS
SleepEasy Therapeutics, Inc.NORTH DAKOTA
Sleep Therapy LLCMINNESOTA
Solara Holdings, LLCDELAWARE
Solara Intermediate, LLCDELAWARE
Solara Medical Supplies, LLCCALIFORNIA
Sound Oxygen Service LLCWASHINGTON
Southern Home Respiratory & Equipment, Inc.VIRGINIA
Specialized Medical Devices, Inc.ALABAMA
Spiro Health Services, LLCDELAWARE
Sunbelt Medical Supply & Oxygen, Inc.FLORIDA
TC Medical Supply, LLCFLORIDA
The 3700 Company, L.L.C.COLORADO
THH Acquisition LLC IDELAWARE
TMS VT, LLCVERMONT
Total Homecare LLCVIRGINIA
Total Respiratory, LLCDELAWARE


Subsidiaries (Alphabetically)State of Inc.
Tricorex, Inc.MISSOURI
TriCounty Medical Equipment and Supply, LLCPENNSYLVANIA
Trinity Healthcare of Winston-Salem, Inc.GEORGIA
Twin Rivers Respiratory Care, Inc.ARKANSAS
Verio Healthcare, Inc.CALIFORNIA
Verus Healthcare LLCDELAWARE
Verus Healthcare Holdings LLCDELAWARE
Vitacare, L.L.C.OKLAHOMA
WeCare Medical Somerset, LLCKENTUCKY
WeCare Medical, LLCKENTUCKY
Wolf Industries, Inc.MISSISSIPPI