Exhibit 15.4

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CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM

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We consent to the incorporation by reference in Registration Statement No. 333-229313 on Form S-8 of our report dated May 14, 2024, relating to the financial statements of 111, Inc., appearing in this Annual Report on Form 20-F for the year ended December 31, 2025.

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/s/ Deloitte Touche Tohmatsu Certified Public Accountants LLP

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Shanghai, China

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April 30, 2026