United States securities and exchange commission logo April 27, 2023 James Coffey Chief Operating Officer and General Counsel ADVENT TECHNOLOGIES HOLDINGS, INC. 500 Rutherford Avenue, Suite 102 Boston, MA 02129 Re: ADVENT TECHNOLOGIES HOLDINGS, INC. Registration Statement on Form S-3 Filed April 21, 2023 File No. 333-271389 Dear James Coffey: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Sarah Sidwell at 202-551-4733 with any questions. Sincerely, Division of Corporation Finance Office of Manufacturing cc: Katherine Blair